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| CAS No.: | 12172-73-5 | |
|---|---|---|
| Name: | Asbestos, Amosite | |
| Molecular Structure: | ||
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| Formula: | N/A | |
| Molecular Weight: | 0 | |
| Synonyms: | Asbestos,grunerite; Grunerite; Amosite; Amosites; Brown asbestos; Grunerite asbestos;Mysorite | |
| Safety: | Confirmed human carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Mutation data reported. | |
Analytical Methods: | For occupational chemical analysis use NIOSH: Fibers, 7400; Asbestos Fibers, 7402. |
|
| PSA: | 0.00000 | |
| LogP: | 0.00000 | |
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Chemistry
Product Name: Asbestos, Amosite (CAS NO.12172-73-5)
Mol File: 12172-73-5.mol
Storage: Treasury ventilated low-temperature drying; separate storage and transportation of raw materials and food
Product Categories: Fibers/Asbestos
Asbestos, Amosite (CAS NO.12172-73-5) is a mineral of the amphibole group of minerals with formula Fe7Si8O22(OH)2. It is the iron endmember of the grunerite-cummingtonite series. It forms as fibrous, columnar or massive aggregates of crystals. The crystals are monoclinic prismatic. The luster is glassy to pearly with colors ranging from green, brown to dark grey. The Mohs hardness is 5 to 6 and the specific gravity is 3.4 to 3.5.
History
Asbestos, Amosite (CAS NO.12172-73-5) was discovered in 1853 and named for Louis Gruner, a Swiss-French chemist who first analysed it. Grunerite is also known commercially by the name amosite from the name Asbestos Mines Of South Africa (AMOSA).
Toxicity Data With Reference
| 1. | cyt-ham:ovr 10 mg/L | CSHCAL Cold Spring Harbor Conferences on Cell Proliferation. 4 (1977),941. | ||
| 2. | sce-ham:ovr 10 mg/L | JEPTDQ Journal of Environmental Pathology and Toxicology. 4 (2-3),(1980),373. | ||
| 3. | msc-ham:lng 10 mg/L | MUREAV Mutation Research. 68 (1979),265. | ||
| 4. | ihl-rat TCLo:11 mg/m3/2Y-I:CAR | BJCAAI British Journal of Cancer. 29 (1974),252. | ||
| 5. | imp-rat TDLo:200 mg/kg:NEO | JJIND8 JNCI, Journal of the National Cancer Institute. 67 (1981),965. |
Consensus Reports
NTP 10th Report on Carcinogens. IARC Cancer Review: Group 1 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 106.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 2 (1973),p. 17.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 14 (1977),p. 11.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 2 (1973),p. 17.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 14 (1977),p. 11.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NTP Carcinogenesis Studies (feed); No Evidence: hamster NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. NTP-TR-249,83 . . EPA Genetic Toxicology Program.
Safety Profile
Confirmed human carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Mutation data reported.
Analytical Methods:
For occupational chemical analysis use NIOSH: Fibers, 7400; Asbestos Fibers, 7402.
Standards and Recommendations
OSHA PEL: TWA 2 million fibers/m3; CL 10 million fibers/m3; Cancer Hazard
ACGIH TLV: TWA 0.1 fibers/cc; Confirmed Human Carcinogen
DFG MAK: DFG TRK: (Fine dust particles that are able to reach the alveolar area of the lung) 1 × 106 fibers/m3 (0.05 mg/m3), applicable when there is more than 2.5% asbestos in the dust
NIOSH REL: (asbestos): 0.1 fb/cc in a 400 L air sample
Analytical Methods
For occupational chemical analysis use NIOSH: Fibers, 7400; Asbestos Fibers, 7402.
Specification
Asbestos, Amosite ,its CAS NO. is 12172-73-5,the synonyms is Amosite ; Amosite asbestos ; Brown asbestos ; CCRIS 354 ; Grunerite asbestos ; HSDB 2957 ; Mysorite ; NCI C60253A ; Asbestos, grunerite .