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| Name |
Aceprometazine |
EINECS | N/A |
| CAS No. | 13461-01-3 | Density | 1.154g/cm3 |
| PSA | 48.85000 | LogP | 4.50700 |
| Solubility | N/A | Melting Point |
N/A |
| Formula | C19H22 N2 O S | Boiling Point | 490.1°Cat760mmHg |
| Molecular Weight | 326.462 | Flash Point | 250.2°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by subcutaneous route. Moderately toxic by ingestion. A flammable liquid. When heated to decomposition it emits toxic vapors of NOx and SOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Ketone,10-[2-(dimethylamino)propyl]phenothiazin-2-yl methyl (7CI,8CI); 1664CB;Aceprometazine; Acepromethazine |
Aceprometazine Chemical Properties
Molecular Structure of Aceprometazine (CAS NO.13461-01-3):
.bmp)
IUPAC Name: 1-[10-[2-(dimethylamino)propyl]phenothiazin-2-yl]ethanone
Empirical Formula: C19H22N2OS
Molecular Weight: 326.4558
Index of Refraction: 1.608
Surface Tension: 44.6 dyne/cm
Density: 1.154 g/cm3
Flash Point: 250.2 °C
Enthalpy of Vaporization: 75.66 kJ/mol
Boiling Point: 490.1 °C at 760 mmHg
Vapour Pressure: 9.4E-10 mmHg at 25°C
Synonyms of Aceprometazine (CAS NO.13461-01-3): aceprometazine ; 1-[10-[2-(Dimethylamino)propyl]-10H-phenothiazin-2-yl]ethanone ; Acepromethazine ; 10-(2-(Dimethylamino)propyl)phenothiazin-2-yl methyl ketone ; Ethanone, 1-(10-(2-(dimethylamino)propyl)-10H-phenothiazin-2-yl)- (9CI) ; Ketone, 10-(2-(dimethylamino)propyl)phenothiazin-2-yl methyl
Aceprometazine Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | oral | 517mg/kg (517mg/kg) | Anesthesie, Analgesie, Reanimation. Vol. 21, Pg. 543, 1964. | |
| mouse | LD50 | subcutaneous | 240mg/kg (240mg/kg) | Anesthesie, Analgesie, Reanimation. Vol. 21, Pg. 543, 1964. |
Aceprometazine Consensus Reports
Reported in AAREAV Anesthesie, Analgesie, Reanimation.
Aceprometazine Safety Profile
Poison by subcutaneous route. Moderately toxic by ingestion. A flammable liquid. When heated to decomposition it emits toxic vapors of NOx and SOx.
Aceprometazine Standards and Recommendations
DOT Classification: 3; Label: Flammable Liquid
Aceprometazine Specification
Aceprometazine (CAS NO.13461-01-3) is a phenothiazine derivative prescription drug with neuroleptic and anti-histamine properties. It is not widely prescribed. It may be used in combination with meprobamate for the treatment of sleep disorders. This combination is available in France under the trade name Mepronizine.
Aceprometazine (CAS NO.13461-01-3) is a corrosive material, flammable,thermal decomposition would release toxic nitrogen oxides and sulfur oxide fumes,it should be stored in low temperature, ventilation, drying environmental conditions,separated with food and raw materials, besides water, carbon oxides and oxidation of toxic carbon dioxide, dry powder, sand, water mist fire extinguishing agent can be used if emergency.
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