The Aminoglutethimide is an organic compound with the formula C₁₃H₁₆N₂O₂. The IUPAC name of this chemical is 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione. With the CAS registry number 125-84-8, it is also named as 2,6-piperidinedione, 3-(4-aminophenyl)-3-ethyl-. The product's categories are Antitumors for Research and Experimental Use; Biochemistry; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals. Besides, it is a white solid, which should be stored in a closed palce at temperature of 2 - 8 °C. It is used as an aromatase inhibitor and blocks adrenal steroidogenesis.

Physical properties about Aminoglutethimide are: (1)ACD/LogP: 1.41; (2)ACD/LogD (pH 5.5): 1.38; (3)ACD/LogD (pH 7.4): 1.41; (4)ACD/BCF (pH 5.5): 6.54; (5)ACD/BCF (pH 7.4): 6.98; (6)ACD/KOC (pH 5.5): 130.94; (7)ACD/KOC (pH 7.4): 139.87; (8)#H bond acceptors: 4; (9)#H bond donors: 3; (10)#Freely Rotating Bonds: 3; (11)Polar Surface Area: 40.62 Å²; (12)Index of Refraction: 1.566; (13)Molar Refractivity: 64.58 cm³; (14)Molar Volume: 197.9 cm³; (15)Polarizability: 25.6×10^-24cm³; (16)Surface Tension: 46.6 dyne/cm; (17)Density: 1.173 g/cm³; (18)Flash Point: 230.4 °C; (19)Enthalpy of Vaporization: 71.75 kJ/mol; (20)Boiling Point: 457.4 °C at 760 mmHg; (21)Vapour Pressure: 1.5E-08 mmHg at 25°C.

Preparation: this chemical can be prepared by 3-ethyl-3-(4-nitro-phenyl)-piperidine-2,6-dione. This reaction will need reagent H₂, catalyst 10percent Pd/C and solvent ethanol. The yield is about 91%.

Uses of Aminoglutethimide: it can be used to produce o-iodoaminoglutethimide by heating. It will need reagent I₂/KI and solvent methanol, H₂O with reaction time of 30 min. The yield is about 70%.

When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system and skin. When you are using it, wear suitable protective clothing. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C1NC(=O)CCC1(c2ccc(N)cc2)CC
(2)InChI: InChI=1/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17)
(3)InChIKey: ROBVIMPUHSLWNV-UHFFFAOYAT
(4)Std. InChI: InChI=1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17)
(5)Std. InChIKey: ROBVIMPUHSLWNV-UHFFFAOYSA-N

The toxicity data is as follows: