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Anilofos

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Anilofos

EINECS 264-756-5
CAS No. 64249-01-0 Density 1.323 g/cm3
PSA 105.97000 LogP 4.98250
Solubility N/A Melting Point 50-51oC
Formula C13H19ClNO3PS2 Boiling Point 443.582 °C at 760 mmHg
Molecular Weight 367.858 Flash Point 222.071 °C
Transport Information UN 3077 Appearance colorless crystal
Safety 60-61 Risk Codes 22-51/53
Molecular Structure Molecular Structure of 64249-01-0 (Anilofos) Hazard Symbols HarmfulXn,DangerousN
Synonyms

Anilofos;Aniloguard;Aniloguard 30EC;Arozin;HOE 30374;HOE 574;

Article Data 5

Anilofos Chemical Properties

Molecular Formula: C13H19ClNO3PS2
Molar mass: 367.85 g/mol
EINECS: 264-756-5
Density: 1.322 g/cm3
Flash Point: 222.1 °C
Index of Refraction: 1.592
Boiling Point: 443.6 °C at 760 mmHg
Vapour Pressure: 4.58E-08 mmHg at 25°C
Melting point: 51.5°C
Water solubility: Solubility in water, 13.6mg / L
Appearance: Pure white needle-like crystal
Solubility: At 25°C, acetone >100%, toluene >100%, chloroform>100%, ethanol>20%, benzene>20% ethyl acetate> 20%, n-hexane 1.2%
Structure of Anilofos (64249-01-0):
             
XLogP3-AA: 3.8
H-Bond Donor: 0
H-Bond Acceptor: 3
IUPAC Name: N-(4-chlorophenyl)-2-dimethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide
Canonical SMILES: CC(C)N(C1=CC=C(C=C1)Cl)C(=O)CSP(=S)(OC)OC
InChI: InChI=1S/C13H19ClNO3PS2/c1-10(2)15(12-7-5-11(14)6-8-12)13(16)9-21-19(20,17-3)18-4/h5-8,10H,9H2,1-4H3 
InChIKey: NXQDBZGWYSEGFL-UHFFFAOYSA-N

Anilofos Uses

 Anilofos (64249-01-0) can be used as herbicides within the absorption of organic phosphorus. Pharmacy absorpted through root, then stop growing and finally make it dead. It can control in rice for monocots, such as barnyard grass, Cyperus difformis, Cyperus grass, Monochoria grass, fescue, steadily grass, flowing grass. And it has a good effect in the early spraying, but can not completely controll while late spraying.

Anilofos Production

It happens alkylation reaction: Take 0.376mol chloroaniline and 2 - bromopropane hybrid for heating, in a certain reaction temperature for several hours.Then cooling, and add sodium hydroxide solution mixing layer, then get reservoir by being washed with water to neutral, and water-layer is extractedwith solvent .At last combine reservoir, and take them off dissolved to get purple liquid 64g,and then obtains 4 - chloro-N-isopropyl-aniline, the yield of 95% ~ 98%.

Anilofos Toxicity Data With Reference

1.    

orl-rat LD50:472 mg/kg

    PEMNDP    Pesticide Manual. 9 (1991),36.
2.    

skn-rat LD50:>2 g/kg

    PEMNDP    Pesticide Manual. 9 (1991),36.
3.    

skn-rbt LD50:>2 g/kg

    FMCHA2    Farm Chemicals Handbook . (Meister Publishing, 37841 Euclid Ave., Willoughy, OH.:  44094)1991,C22.
4.    

unr-pgn LDLo:500 mg/kg

    FMCHA2    Farm Chemicals Handbook . (Meister Publishing, 37841 Euclid Ave., Willoughy, OH.:  44094)1991,C22.
5.    

unr-ckn LDLo:1480 mg/kg

    FMCHA2    Farm Chemicals Handbook . (Meister Publishing, 37841 Euclid Ave., Willoughy, OH.:  44094)1991,C22.
6.    

orl-qal LD50:2339 mg/kg

    PEMNDP    Pesticide Manual. 9 (1991),36.
7.    

orl-rat TDLo:850 mg/kg

    TXCYAC    Toxicology. 165 (2001),87.

Anilofos Safety Profile

Moderately toxic by ingestion and skin contact. When heated to decomposition it emits toxic vapors of NOx, POx, SOx, and Cl-.
Hazard Codes: Xn;N
Risk Statements:
22:  Harmful if swallowed 
51:  Toxic to aquatic organisms
53:  May cause long-term adverse effects in the aquatic environment
Safety Statements:
60:  This material and/or its container must be disposed of as hazardous waste
61:  Avoid release to the environment. Refer to special instructions safety data sheet

Anilofos Specification

 Anilofos (64249-01-0) also can be called for Aniloguard ; S-(2-((4-Chlorophenyl)(1-methylethyl)amino)-2-oxoethyl) O,O-dimethyl phosphorodithioate ;and; Dithiophosphate de S-{2-[(4-chlorophényl)(isopropyl)amino]-2-oxoéthyle} et de O,O-diméthyle .

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