Welcome to LookChem.com Sign In|Join Free
  • or
Home > Pharmaceutical > 105219 > 

105219-56-5
Refine

Refine

Country

Business Type

Certificate

Display

Products Categories

Basic Information
CAS No.: 105219-56-5
Name: Apafant
Molecular Structure:
Molecular Structure of 105219-56-5 (Apafant)
Formula: C22H22 Cl N5 O2 S
Molecular Weight: 455.968
Synonyms: Morpholine,4-[3-[4-(2-chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-oxopropyl]-(9CI); 6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine, morpholine deriv.;Apafant; WEB 2086BS; Web 2086
Density: 1.48
Melting Point: 186-188°C
Boiling Point: 720.2°Cat760mmHg
Flash Point: 389.4°C
PSA: 100.85000
LogP: 2.80650
Related products
Hot Products
  • Display:default sort

    New supplier

  • Apafant

  • Casno:

    105219-56-5

    Apafant

    Min.Order: 1 Gram

    FOB Price:  USD $ 150.0-3500.0

    LIDE PHARMACEUTICALS LTD.was established in Apr.,2010. It is located in Jiangbei New District, Pukou District, Nanjing, which is the capital of total six dynasties in the Chinese history. We are a company that provides customized development and prod

    LIDE PHARMACEUTICALS LTD.was established in Apr.,2010 located Nanjing. We are a company that provides customized development and production services (CDMO) for global chemical and

  •  LIDE PHARMACEUTICALS LIMITED

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-25-58409506

    Address:N0.2-309 2/F Chungking Express Nos.36 Nathan Road，Kowloon, HK

       Inquiry Now

  • Apafant;105219-56-5

  • Casno:

    105219-56-5

    Apafant;105219-56-5

    Min.Order: 10 Metric Ton

    FOB Price:  USD $ 0.0-0.0

    1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

    Founded in 2011, Amadis Chemical Company Limited is an innovative manufacturer of chemical products and technical service providers. Our business includes sales, manufacture, and s

  •  Amadis Chemical Co., Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-571-89925085

    Address:Watts Cosine.No.166.Xiangmao Road.

       Inquiry Now

  • Manufacturer supply CAS 105219-56-5 with best quality

  • Casno:

    105219-56-5

    Manufacturer supply CAS 105219-56-5 with best quality

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 139.0-210.0

    WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

    Zhuo Zhou Wen Xi Import and Export Co., Ltd. is a company mainly engaged in the export of pharmaceutical raw materials. Its parent company is （Wen Xi Pharma）, including three subs

  •  Zhuozhou Wenxi import and Export Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-13111626072

    Address:Room 1710, Baoxin International Phase I, 19 Guanyun East Road, Zhuozhou, Hebei

       Inquiry Now

  • Apafant

  • Casno:

    105219-56-5

    Apafant

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0

    Hello, dear friend! Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by email in time. product quality 1.The product quality h

    Suzhou senfeida Chemical Co., Ltd. is located in Hushuguan economic and Technological Development Zone, Suzhou high tech Zone. It is a civilian chemical enterprise that produces an

  •  Suzhou Senfeida Chemical Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:186-624-33356

    Address:Hushuguan Economic and Technological Development Zone, Suzhou High-tech Zone

       Inquiry Now

  • WEB 2086

  • Casno:

    105219-56-5

    WEB 2086

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.Appearanc

    BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-info

  •  BOC Sciences

    United States  |  Contact Details

    Business Type:Trading Company

    Tel:1-631-485-4226

    Address:Ramsey Road

       Inquiry Now

  • Apafant

  • Casno:

    105219-56-5

    Apafant

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Apafant Application:powder or liquid

    Hangyu Biotech is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and O

  •  Zibo Hangyu Biotechnology Development Co., Ltd

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-15965530500

    Address:Room1701, Tianxing Building,Licheng district, jinan, Shandong, China

       Inquiry Now

  • Apafant

  • Casno:

    105219-56-5

    Apafant

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Shanghai Macklin Biochemical Co., Ltd is a leading manufacturer and supplier for high-end research reagents. We aim to provide technology and industrial customers throughout the wo

  •  Shanghai Macklin Biochemical Co., Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-021-51821862

    Address:5F No. Bldg10, 88 Darwin road, Pudong, Shanghai, P.R. China, 201206

       Inquiry Now

  • Apafant

  • Casno:

    105219-56-5

    Apafant

    Min.Order: 0 Metric Ton

    FOB Price:  USD $ 0.0-0.0

    Molecular Structure of Apafant (CAS No.105219-56-5): Molecular Formula: C22H22ClN5O2S Molecular Weight: 455.9604 CAS No: 105219-56-5 H bond acceptors: 7 H bond donors: 0 Freely Rotating Bonds: 4 Polar Surface Area: 100.85 Å2

    MC is a comprehensive chemical enterprise which manufacture and supply inorganic/organic chemicals, polymer,waste oil and so on. It located in the beautiful coastal city Tianjin, C

  • MENGNA

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:18698110882

    Address:1303 No2 building,LuoMa Garden,YongAn Road,Hexi District,Tianjin city

       Inquiry Now

  • Apafant

  • Casno:

    105219-56-5

    Apafant

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Zhejiang Jiuzhou Chem Co.,Ltd is a foreign trading company, specializing in developing and producing Organic intermediate . It has its own factory, which procures itself a competitive edge in market. For many years, our company has won many clients&

    Zhejiang Jiuzhou Chem Co.,Ltd is a market-oriented and innovation-driven biopharmaceutical company. The company is focusing on the R&D, manufacturing and sales of pharmaceutical pr

  • ZHEJIANG JIUZHOU CHEM CO.,LTD

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86 19334956669-956-669

    Address:Waisha Road,Jiaojiang

       Inquiry Now

  • Apafant

  • Casno:

    105219-56-5

    Apafant

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0

    Henan Coreychem co., LTD focus on high complex new type intermediates and fine chemical custom synthesis,scale-up production and rare chemicals trade.Product category including Intermediates&API,Catalyst and Electronic Chemicals.Covering 811 square m

    Career Henan Chemical Co, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded t

  • Career Henan Chemical Co

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-371-86658258

    Address:Building 10 of Innovation Park, East District of the National University Science Park

       Inquiry Now

  • Apafant

  • Casno:

    105219-56-5

    Apafant

    Min.Order: 1 Milligram

    FOB Price:  USD $ 10.0-10.0

    Q1:Are you manufacturer or trading company? A1: Manufacturer. Q2: Can I get some sample? A2: Yes Q3: What's your MOQ? A3: Our MOQ is flexible.different price for different quantity Q4: Is there a discount? A4: Of course, welcome to contact us.

    WEIFANG YANGXU GROUP Co., Ltd was founded in 1996. More than 20 years full efforts, YANGXU chemical has grown to be a large enzyme peptide chemical enterprise, specializing in expl

  • weifang yangxu group co.,ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+08613666361637--

    Address:No 5.dongfeng east street.gaoxin district.weifang city.

       Inquiry Now

  • 105219-56-5

  • Casno:

    105219-56-5

    105219-56-5

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    intermediateAppearance:powder Storage:Normal temperature Package:1kg/25kg/customized Application:intermediate Transportation:By Ship/Air

    Shanghai Petrochemical Co.,Ltd is committed to the development, production and customized sales of a series of fine chemicals such as pharmaceutical raw materials, pharmaceutical i

  • Shanghai Petrochemical Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:15252503096

    Address:Room 102,Purple Crystal Court, Lane 398,#35,Sunnong Road,Pudong New Area,

       Inquiry Now

  • SH1809

  • Casno:

    105219-56-5

    SH1809

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    intermediateAppearance:powder Storage:Normal temperature Package:1kg/25kg/customized Application:intermediate Transportation:By Ship/Air Port:any port of china

    yierdechem is a young and potential team, with about ten years experiences in the field of pharmaceutical intermediate and fine chemicals, yierdechem has established solid business

  • Hangzhou Yierdechem Co. Ltd

    China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:+86-571-86904883

    Address:903,zhijiang Minglou, Xiasha EDA, Hangzhou City 310018,P.R.China

       Inquiry Now

  • Apafant

  • Casno:

    105219-56-5

    Apafant

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Professional Application:intermediates

    Shanghai shinso-pharm Technology Co., Ltd. is a high-tech enterprise mainly engaged in the research and sales of amino acid derivatives, heterocyclic compounds, organic synthetic b

  • Shanghai Shinso-pharm Technology Co. , Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-021-62165619

    Address:4th floor, building 9,20 Gold Industrial Park Road, Zhengdian Street, Jiangxia District, Wuhan, Hubei Province

       Inquiry Now

  • Apafant

  • Casno:

    105219-56-5

    Apafant

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    high purity Application:Drug intermediates Materials intermediates and active molecules

    Novachemistry offers a broad range of specialty chemicals and customized synthesis services to a range of pharmaceutical, agrochemical and biochemical industries. Novachemistry has

  • NovaChemistry

    United Kingdom  |  Contact Details

    Business Type:Trading Company

    Tel:+44 (0)208 191 7890

    Address:Unit11, Ark Business Centre, Gorden Road, Loughborough, United Kingdom

       Inquiry Now

  • Apafant

  • Casno:

    105219-56-5

    Apafant

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Toronto Research Chemicals Inc. (TRC) is a world leader in the manufacture of complex organic chemicals for biomedical research. We supply products

  • Toronto Research Chemicals

    Canada  |  Contact Details

    Business Type:Trading Company

    Tel:(416) 665-9696, 800-727-9240

    Address:2 Brisbane Rd.,North York, On.Canada M3J 2J8

       Inquiry Now

  • Total:20 Page 1 of 1 1
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 105219-56-5

Chemistry

Molecular Structure of Apafant (CAS No.105219-56-5):
 
Molecular Formula: C22H22ClN5O2S
Molecular Weight: 455.9604
CAS No: 105219-56-5
H bond acceptors: 7
H bond donors: 0
Freely Rotating Bonds: 4
Polar Surface Area: 100.85 Å2
Index of Refraction: 1.733
Molar Refractivity: 122.73 cm3
Molar Volume: 306.3 cm3
Surface Tension: 60.1 dyne/cm
Density: 1.48 g/cm3
Flash Point: 389.4 °C
Enthalpy of Vaporization: 105.22 kJ/mol
Boiling Point: 720.2 °C at 760 mmHg
Vapour Pressure: 1.36E-20 mmHg at 25°C
Classification Code: Cardiovascular Agents;Drug / Therapeutic Agent;Fibrin Modulating Agents;Fibrinolytic agents;Hematologic Agents;Platelet activating factor antagonist;Platelet aggregation inhibitors;Reproductive Effect
Systematic Name: 3-[4-(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-(morpholin-4-yl)propan-1-one 
InChI: InChI=1/C22H22ClN5O2S/c1-14-25-26-19-13-24-21(16-4-2-3-5-18(16)23)17-12-15(31-22(17)28(14)19)6-7-20(29)27-8-10-30-11-9-27/h2-5,12H,6-11,13H2,1H3
InChIKey: JGPJQFOROWSRRS-UHFFFAOYAU
Std. InChI: InChI=1S/C22H22ClN5O2S/c1-14-25-26-19-13-24-21(16-4-2-3-5-18(16)23)17-12-15(31-22(17)28(14)19)6-7-20(29)27-8-10-30-11-9-27/h2-5,12H,6-11,13H2,1H3
Std. InChIKey: JGPJQFOROWSRRS-UHFFFAOYSA-N
Product Categories: Intermediates Fine Chemicals;Pharmaceuticals;Sulfur Selenium Compounds;PAF receptor

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 400mg/kg (400mg/kg)   United States Patent Document. Vol. #4968794,
mouse LD50 oral 3gm/kg (3000mg/kg)   United States Patent Document. Vol. #4968794,

Specification

  Apafant (CAS No.105219-56-5), its synonyms are 4-(3-(4-(o-Chlorophenyl)-9-methyl-6H-thieno(3,2-f)-s- ; Triazolo(4,3-a)(1,4)diazepin-2-yl)propionyl)morpholine ; 3-[4-(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-(4-morpholinyl)-1-propanone .