- Apazone
- Apazone dihydrate
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| Name |
Apazone |
EINECS | N/A |
| CAS No. | 13539-59-8 | Density | 1.29g/cm3 |
| PSA | 60.13000 | LogP | 2.48470 |
| Solubility | 147.2mg/L(35 oC) | Melting Point |
228° |
| Formula | C16H20 N4 O2 | Boiling Point | 438°Cat760mmHg |
| Molecular Weight | 300.36 | Flash Point | 218.7°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Moderately toxic by ingestion, intraperitoneal and intravenous routes. When heated to decomposition it emits toxic fumes of NOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
3-Dimethylamino-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1,2,4-benzotriazine;5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo[1,2-a][1,2,4]benzotriazine-1,3(2H)-dione;AHR 3018; Apazone; Azapropazone; Cinnamin; Cinnopropazone; Mi 85; NSC 102824;Prolixan; Sinnamin |
Apazone Chemical Properties
IUPAC Name: 5-(Dimethylamino)-9-methyl-2-propylpyrazolo[1,2-a][1,2,4]benzotriazine-1,3-dione
Molecular Formula: C16H20N4O2
Molecular Weight: 300.40g/mol
Density:1.29g/cm3
Boiling Point: 438°C at 760mmHg
Flash Point: 218.7°C
Freely Rotating Bonds: 3
Polar Surface Area: 56.22 Å2
Index of Refraction: 1.646
Molar Refractivity: 84.52 cm3
Molar Volume: 232.8 cm3
Polarizability: 33.5 ×10-24cm3
Surface Tension: 47.4 dyne/cm
Enthalpy of Vaporization: 69.47 kJ/mol
Vapour Pressure: 7.16E-08 mmHg at 25°C
The Cas Register Number of Apazone is 13539-59-8 .The chemical synonyms of Apazone (CAS No.13539-59-8 ) are Azapropazone impurity c bp(crm standard) ; Azapropazone impurity b bp standard(crm standard) ; Azapropazone bp standard(crm standard) ; Azapropazone impurity standard bp(crm standard) ; Azapropazone impurity a bp(crm standard) ; Azapropazone assay standard bp(crm standard) ; Azapropazone impurity b bp(crm standard) ; Azapropazone impurity a bp standard(crm standard .Product categories of Apazone (CAS No.13539-59-8 ) is
.
Apazone Uses
It is used as analgesic and anti-inflammatory agent.
Apazone Toxicity Data With Reference
| 1. | orl-rat LD50:1800 mg/kg | OYYAA2 Oyo Yakuri. Pharmacometrics. 15 (1978),41. | ||
| 2. | ipr-rat LD50:650 mg/kg | CMROCX Current Medical Research and Opinion. 4 (1976),17. | ||
| 3. | ivn-rat LD50:660 mg/kg | CMROCX Current Medical Research and Opinion. 4 (1976),17. | ||
| 4. | orl-mus LD50:1080 mg/kg | CMROCX Current Medical Research and Opinion. 4 (1976),17. | ||
| 5. | ipr-mus LD50:920 mg/kg | CMROCX Current Medical Research and Opinion. 4 (1976),17. | ||
| 6. | ivn-mus LD50:680 mg/kg | CMROCX Current Medical Research and Opinion. 4 (1976),17. | ||
| 7. | ivn-cat LD50:500 mg/kg | CMROCX Current Medical Research and Opinion. 4 (1976),17. |
Apazone Safety Profile
Moderately toxic by ingestion, intraperitoneal and intravenous routes. When heated to decomposition it emits toxic fumes of NOx.
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