Product Name: Azathioprine (CAS NO.446-86-6)
Molecular Formula: C₉H₇N₇SO₂

Molecular Weight: 277.26
EINECS: 207-175-4
Melting point:  243-244°C
Storage temp.:  Freezer
Water Solubility:  <0.1 g/100 mL at 23 °C
Merck: 902
Index of Refraction: 1.923 
Molar Refractivity: 68.88 cm³ 
Surface Tension: 98.3 dyne/cm 
Density: 1.9 g/cm³ 
Flash Point: 368.5 °C 
Enthalpy of Vaporization: 96.93 kJ/mol 
Boiling Point: 685.7 °C at 760 mmHg 
Vapour Pressure: 7.1E-18 mmHg at 25°C
Structure Descriptors of Product Name: Azathioprine (CAS NO.446-86-6):
  IUPAC Name: 6-(3-methyl-5-nitroimidazol-4-yl)sulfanyl-7H-purine
  Canonical SMILES: CN1C=NC(=C1SC2=NC=NC3=C2NC=N3)[N+](=O)[O-]
  InChI: InChI=1S/C9H7N7O2S/c1-15-4-14-7(16(17)18)9(15)19-8-5-6(11-2-10-5)12-3-13-8/h2-4H,1H3,(H,10,11,12,13) 
  InChIKey: LMEKQMALGUDUQG-

Azathioprine (CAS NO.446-86-6) is an immunosuppressant which is commonly used in organ transplantation, autoimmune disease or Inflammatory Bowel Disease (IBD). It is also used in multiple sclerosis, autoimmune hepatitis and restrictive lung disease. It's also active as disease modifying antirheumatic drug (DMARD).

RTECS:  UO8925000

NTP 10th Report on Carcinogens. IARC Cancer Review: Group 1 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 119.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 26 (1981),p. 47.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 26 (1981),p. 47.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NCI Carcinogenesis Studies (ipr); No Evidence: rat CANCAR    Cancer. 40 (1977),1935. ; Clear Evidence: mouse CANCAR    Cancer. 40 (1977),1935. . EPA Genetic Toxicology Program.

Confirmed human carcinogen producing bladder tumors and leukemia. Poison by subcutaneous, intradermal, and intraperitoneal routes. Moderately toxic by ingestion. Human systemic effects: liver changes, hypermotility, diarrhea, nausea or vomiting, increased body temperature, BP lowering, decreased urine volume or anuria, normocytic anemia, bone marrow changes. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NO_x and SO_x. An immunosuppressant.

Hazard Codes:  Xi,T,Xn
Risk Statements:  45-22-36/37/38-20/21/22 
R45:May cause cancer. 
R22:Harmful if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin. 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements:  53-22-26-36/37-45-36 
S53:Avoid exposure - obtain special instructions before use. 
S22:Do not breathe dust. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37:Wear suitable protective clothing and gloves. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S36:Wear suitable protective clothing.
Hazard Note:  Irritant

Azathioprine (CAS NO.446-86-6) is also named as 6-((1-Methyl-4-nitro-1h-imidazol-5-yl)thio)-1h-purin ; 6-((1-Methyl-4-nitroimidazol-5-yl)thio)-purin ; 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine ; 6-(1-Methyl-4-nitro-5-imidazolythio)-9H-pur-ine ; 6-(1-Methyl-4-nitroimidazol-5-ylthio)purin ; 6-(1-Methyl-p-nitro-5-imidazolyl)-thiopurine ; Azamun and so on.