Basic Information | Post buying leads | Suppliers |
Name |
Basic Blue 17 |
EINECS | 202-146-2 |
CAS No. | 92-31-9 | Density | N/A |
PSA | 70.39000 | LogP | 1.27240 |
Solubility | 3.82 g/100 mL | Melting Point |
>200℃ |
Formula | C15H16ClN3S | Boiling Point | N/A |
Molecular Weight | 305.831 | Flash Point | N/A |
Transport Information | N/A | Appearance | green powder |
Safety | 22-24/25 | Risk Codes | 36/37/38 |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
3-Amino-7-(dimethylamino)-2-methylphenazathioniumchloride;Phenothiazin-5-ium,3-amino-7-(dimethylamino)-2-methyl-, chloride (8CI,9CI);3-Amino-7-(dimethylamino)-2-methylphenothiazin-5-ium chloride;Blutene;Blutene chloride;Phenothiazinium, 3-amino-7-(dimethylamino)-2-methyl-, chloride;Dimethyltoluthionine chloride; |
Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.
The Tolonium chloride with CAS registry number of 92-31-9 is also called Phenothiazin-5-ium,3-amino-7-(dimethylamino)-2-methyl-,chloride (1:1). The systematic name is 3-amino-7-(dimethylamino)-2-methylphenothiazin-5-ium chloride. Its EINECS registry number is 202-146-2. In addition, the molecular formula is C15H16ClN3S and the molecular weight is 305.83.
Physical properties about Tolonium chloride are: (1)#H bond acceptors: 3; (2)#H bond donors: 2; (3)#Freely Rotating Bonds: 2; (4)Polar Surface Area: 42.15 Å2; (5)log P (octanol-water): 5.260; (6)Water Solubility: 3.82E+04 mg/L; (7)Atmospheric OH Rate Constant: 2.66E-10 cm3/molecule-sec.
Uses of Tolonium chloride: it can be used as used as a hemostatic, a biological stain, and a dye for wool and silk. And it has also been used as a diagnostic aid for oral and gastric neoplasms. In addition, it can be used to determine DNA and RNA in histochemistry.
You can still convert the following datas into molecular structure:
(1)SMILES: [Cl-].CN(C)c1ccc2nc3cc(C)c(N)cc3[s+]c2c1
(2)InChI: InChI=1/C15H16N3S.ClH/c1-9-6-13-15(8-11(9)16)19-14-7-10(18(2)3)4-5-12(14)17-13;/h4-8H,16H2,1-3H3;1H/q+1;/p-1
(3)InChIKey: HNONEKILPDHFOL-REWHXWOFAY
The toxicity data is as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
domestic animals - goat/sheep | LD50 | intravenous | 10mg/kg (10mg/kg) | Veterinary and Human Toxicology. Vol. 38, Pg. 329, 1996. | |
man | TDLo | unreported | 43mg/kg/6D (43mg/kg) | GASTROINTESTINAL: NAUSEA OR VOMITING BLOOD: OTHER CHANGES | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 597, 1969. |
mouse | LD50 | intravenous | 27560ug/kg (27.56mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION | Stanford Medical Bulletin. Vol. 9, Pg. 96, 1951. |
mouse | LD50 | unreported | 28mg/kg (28mg/kg) | Journal of Medicinal Chemistry. Vol. 17, Pg. 902, 1974. | |
rabbit | LD50 | intravenous | 13440ug/kg (13.44mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION | Stanford Medical Bulletin. Vol. 9, Pg. 96, 1951. |
rat | LD50 | intraperitoneal | 215mg/kg (215mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 204, Pg. 288, 1947. | |
rat | LD50 | intravenous | 28930ug/kg (28.93mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Stanford Medical Bulletin. Vol. 9, Pg. 96, 1951. |