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Benzbromarone

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Benzbromarone

EINECS 222-630-7
CAS No. 3562-84-3 Density 1.709 g/cm3
PSA 50.44000 LogP 5.45680
Solubility N/A Melting Point 161 - 163oC
Formula C17H12Br2O3 Boiling Point 514.1 °C at 760 mmHg
Molecular Weight 424.088 Flash Point 264.7 °C
Transport Information UN 2811 6.1/PG 3 Appearance White to off-white crystalline powder
Safety 36 Risk Codes 22
Molecular Structure Molecular Structure of 3562-84-3 (BENZBROMARONE) Hazard Symbols HarmfulXn
Synonyms

Ketone,3,5-dibromo-4-hydroxyphenyl 2-ethyl-3-benzofuranyl (6CI,7CI,8CI);2-Ethyl-3-(3,5-dibromo-4-hydroxybenzoyl)benzofuran;3,5-Dibromo-4-hydroxyphenyl2-ethyl-3-benzofuranyl ketone;Azubromaron;Benzbromaron;Besuric;Desuric;Max-Uric;Minuric;NSC 85433;Normurat;Uricovac;Urinorm;

Article Data 8

Benzbromarone Chemical Properties

IUPAC Name: (3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran-3-yl)methanone
The MF of (3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran-3-yl)methanone (3562-84-3) is C17H12Br2O3.

                                                  
The MW of (3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran-3-yl)methanone (3562-84-3) is 424.08.
Synonyms of (3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran-3-yl)methanone (3562-84-3): (3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)methanone ; 2-Ethyl-3-(3,5-dibromo-4-hydroxybenzoyl)benzofuran ; 2-Ethyl-3-benzofuranyl 4-Hydroxy-3,5-dibromophenyl Ketone ; 3,5-Dibromo-4-hydroxyphenyl 2-Ethyl-3-benzofuranyl Ketone ; 2-Ethyl-3-benzofuryl 3,5-dibromo-4-hydroxyphenyl Ketone 
Product Categories: Heterocyclic Compound
Index of Refraction: 1.673 
EINECS: 222-630-7
Density: 1.709 g/ml 
Flash Point: 264.7 °C
Boiling Point: 514.1 °C
Storage temp: 2-8°C

Benzbromarone Uses

  (3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran-3-yl)methanone (3562-84-3) is used for the treatment of gout, hyperuricemia.

Benzbromarone Toxicity Data With Reference

1.    

orl-rat LD50:248 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 10 (1979),232.
2.    

ipr-rat LD50:239 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 10 (1979),232.
3.    

scu-rat LD50:1230 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 10 (1979),232.
4.    

orl-mus LD50:618 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 10 (1979),232.
5.    

ipr-mus LD50:146 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 6 (1972),341.
6.    

scu-mus LD50:4120 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 10 (1979),232.
7.    

ivn-mus LD50:77 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 6 (1972),341.

Benzbromarone Consensus Reports

Reported in EPA TSCA Inventory.

Benzbromarone Safety Profile

Poison by ingestion, intravenous, and intraperitoneal routes. Moderately toxic by subcutaneous route. Experimental teratogenic and reproductive effects. A uricosuric agent which promotes the excretion of uric acid in the urine. A flammable liquid. When heated to decomposition it emits toxic fumes of Br. See also KETONES.
Safety information of (3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran-3-yl)methanone (3562-84-3):
Hazard Codes  Xn
Risk Statements 
22  Harmful if swallowed
Safety Statements 
36  Wear suitable protective clothing
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  OB1804200
HazardClass  6.1(b)
PackingGroup  III

Benzbromarone Standards and Recommendations

DOT Classification:  3; Label: Flammable Liquid

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