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Benzydamine

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Name

Benzydamine

EINECS 211-388-8
CAS No. 642-72-8 Density 1.08g/cm3
PSA 30.29000 LogP 3.41510
Solubility N/A Melting Point 167-170 °C
Formula C19H23 N3 O Boiling Point 474.4oC at 760 mmHg
Molecular Weight 309.411 Flash Point 240.7oC
Transport Information N/A Appearance N/A
Safety Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx. Risk Codes N/A
Molecular Structure Molecular Structure of 642-72-8 (Benzydamine) Hazard Symbols N/A
Synonyms

1H-Indazole,1-benzyl-3-[3-(dimethylamino)propoxy]- (7CI,8CI); 1-Benzyl-3-(g-dimethylaminopropoxy)-1H-indazole;1-Benzyl-3-[3-(dimethylamino)propoxy]-1H-indazole;1-Benzyl-3-[3-(dimethylamino)propoxy]indazole;1-Benzyl-3-dimethylaminopropoxy-1H-indazole; Benzidamine; Benzindamine;Benzydamine

 

Benzydamine Chemical Properties

IUPAC Name: 3-(1-benzylindazol-3-yl)oxy-N,N-dimethylpropan-1-amine
Synonyms: 1-Benzyl-3-[3-(dimethylamino)propoxy]-1H-indazole ; [3-(1-Benzyl-1H-indazol-3-yloxy)propyl]dimethylamine
Molecular Structure of Benzindamine (CAS NO. 642-72-8) :
Molecular Formula of Benzindamine (CAS NO. 642-72-8) : C19H23N3O
Molecular Weight of Benzindamine (CAS NO. 642-72-8) : 309.40
CAS NO: 642-72-8
EINECS : 211-388-8
Index of Refraction: 1.579
Surface Tension: 40.3 dyne/cm
Density: 1.08 g/cm3
Flash Point: 240.7 °C
Enthalpy of Vaporization: 73.77 kJ/mol
Boiling Point: 474.4 °C at 760 mmHg
Vapour Pressure: 3.64E-09 mmHg at 25°C

Benzydamine Uses

 Benzindamine (CAS NO. 642-72-8) is usd as anti-inflammatory analgesics.

Benzydamine Toxicity Data With Reference

1.    

orl-rat LD50:9500 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 22 (1972),711.
2.    

orl-mus LD50:460 mg/kg

    JMCMAR    Journal of Medicinal Chemistry. 15 (1972),923.
3.    

ipr-mus LD50:109 mg/kg

    JMCMAR    Journal of Medicinal Chemistry. 15 (1972),471.
4.    

scu-mus LD50:445 ng/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 6 (1972),1285.
5.    

ivn-mus LD50:25 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 6 (1972),1285.

Benzydamine Safety Profile

Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx.

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