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Basic Information
CAS No.: 54856-23-4
Name: Betahistine mesylate
Molecular Structure:
Molecular Structure of 54856-23-4 (Betahistine mesylate)
Formula: C8H12N2.2CH4O3S
Molecular Weight: 232.304
Synonyms: methanesulfonic acid; N-methyl-2-pyridin-2-yl-ethanamine;Prestwick_838;Betahistine mesilate;Suzutolon (TN);Suzutolon;Betahistine mesilate (JP14);Betahistine Dimesilate;2-(ethylammonio)-N-methylpyridinium dimethanesulphonate;N-METHYL-2-PYRIDINE ETHANAMINE DIMETHANESULFONATE;
EINECS: 259-377-7
Melting Point: 112°C
Boiling Point: 210.9 °C at 760 mmHg
Flash Point: 96.7 °C
Solubility: almost transparency
Appearance: COA
PSA: 150.42000
LogP: 2.40400
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Chemistry

IUPAC Name: Methanesulfonic acid; N-methyl-2-pyridin-2-ylethanamine
Synonyms: N-Methyl-2-pyridineethanamindimethanesulfonate ; 2-[2-(Methylamino)ethyl]pyridine methanesulfonate ; Betahistine mesilate ; Betahistine mesylate ; Betahistine methanesulfonate ; Betahistine dimesylate ; Betahistine dimethanesulfonate ; N-Methyl-2-pyridineethylamine dimethanesulphonate
Molecular Structure of Betahistine mesylate (CAS NO.54856-23-4) :
Molecular Formula-: C8H12N2.2(CH4O3S)
Molecular Weight-: 328.40
CAS NO: 54856-23-4
EINECS: 259-377-7
Melting point: 112 °C 
Flash Point: 96.7 °C
Enthalpy of Vaporization: 44.72 kJ/mol
Boiling Point: 210.9 °C at 760 mmHg
Vapour Pressure: 0.187 mmHg at 25 °C 
Classification Code: Drug / Therapeutic Agent

Uses

 Betahistine mesylate (CAS NO.54856-23-4) is used for vertigo, dizziness and feeling, Meniere's disease, Meniere's syndrome, dizziness.

Toxicity Data With Reference

1.    

orl-rat LD50:3030 mg/kg

     NIIRDN    Drugs in Japan. Ethical Drugs, 6th Edition 1982. 6 (1982),750.
2.    

scu-rat LD50:940 mg/kg

     NIIRDN    Drugs in Japan. Ethical Drugs, 6th Edition 1982. 6 (1982),750.
3.    

ivn-rat LD50:604 mg/kg

     NIIRDN    Drugs in Japan. Ethical Drugs, 6th Edition 1982. 6 (1982),750.
4.    

orl-mus LD50:500 mg/kg

     NIIRDN    Drugs in Japan. Ethical Drugs, 6th Edition 1982. 6 (1982),750.
5.    

scu-mus LD50:1630 mg/kg

     NIIRDN    Drugs in Japan. Ethical Drugs, 6th Edition 1982. 6 (1982),750.
6.    

ivn-mus LD50:505 mg/kg

     NIIRDN    Drugs in Japan. Ethical Drugs, 6th Edition 1982. 6 (1982),750.
7.    

orl-gpg LD50:1400 mg/kg

     NIIRDN    Drugs in Japan. Ethical Drugs, 6th Edition 1982. 6 (1982),750.
8.    

scu-gpg LD50:120 mg/kg

     NIIRDN    Drugs in Japan. Ethical Drugs, 6th Edition 1982. 6 (1982),750.
9.    

ivn-gpg LD50:22,900 µg/kg

     NIIRDN    Drugs in Japan. Ethical Drugs, 6th Edition 1982. 6 (1982),750.

Safety Profile

Poison by subcutaneous route. Moderately toxic by ingestion and other routes. When heated to decomposition it emits toxic fumes of NOx and SOx.
RTECS: UT2970200