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Basic Information
CAS No.: 9060-10-0
Name: Bleomycin B2
Molecular Structure:
Molecular Structure of 9060-10-0 (Bleomycin B2)
Formula: C55H84 N20 O21 S2
Molecular Weight: 1425.53
Synonyms: BleomycinB2; Dehydrophleomycin D1; Phleomycin D2; Zhengguangmycin B2
Density: 1.79g/cm3
Boiling Point: °Cat760mmHg
Flash Point: °C
Safety: Poison by intratracheal route. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx. See other bleomycin entries.
PSA: 745.45000
LogP: -1.78960
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Chemistry

IUPAC Name: [(2R,3S,4S,5R,6R)-2-[(2R,3S,4S,5S,6S)-2-[(1R,2S)-2-[[6-Amino-2-[(1S)-3-amino-1-[[(2S)-2,3-diamino-3-oxopropyl]amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[(2R,3S,4S)-5-[[(2S,3R)-1-[2-[4-[4-[(diaminomethylideneamino)butylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-ylamino]-3-hydroxy-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6 hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate
Molecular Formula: C55H84N20O21S2
Molecular Weight: 1425.71g/mol
Density: 1.79g/cm3
The Cas Register Number of Bleomycin B2 is 9060-10-0 .The chemical synonyms of Bleomycin B2 (CAS NO.9060-10-0) are Bleomycin B2 ; Blemoycin bz ; Dehydrophleomycin d1 ; N1-[4-[(aminoiminomethyl)amino]butyl]bleomycinamide ; N1-[4-[[amino(imino)methyl]amino]butyl]bleomycinamide ; Phleomycin D2 ; Zhengguanmycin B2 .The molecular structure of  Bleomycin B2 (CAS NO.9060-10-0) is.

Uses

 Bleomycin B2 (CAS NO.9060-10-0) can be used in organic synthesis.

Toxicity Data With Reference

1.    

mmo-sat 1 µg/plate

     MUREAV    Mutation Research. 117 (1983),9.
2.    

dnd-omi 100 mg/L

     JANTAJ    Journal of Antibiotics. 28 (1975),537.
3.    

dnd-omi 10,700 pmol/L

     CNREA8    Cancer Research. 40 (1980),4173.
4.    

itr-mus LDLo:14 µg/kg

     TXAPA9    Toxicology and Applied Pharmacology. 56 (1980),326.

Safety Profile

Poison by intratracheal route. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx. See other bleomycin entries.

Specification

The extinguishing agent of Bleomycin B2 (CAS NO.9060-10-0) are dry powder, foam, sand, carbon dioxide, water mist.