1000198-80-0

Basic information

• Product Name: 3-(3-fluorobenzyl)pyrrolidine
• Synonyms: 3-(3-fluorobenzyl)pyrrolidine;3-[(3-FLUOROPHENYL)METHYL]-PYRROLIDINE;3-[(3-Fluorophenyl)methyl]-pyrrolidine HCl
• CAS NO: 1000198-80-0
• Molecular Formula: C11H14FN
• Molecular Weight: 179
• Product Categories: CHIRAL CHEMICALS
• Mol File: 1000198-80-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(3-fluorobenzyl)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-fluorobenzyl)pyrrolidine(1000198-80-0)
• EPA Substance Registry System: 3-(3-fluorobenzyl)pyrrolidine(1000198-80-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 1000198-80-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Development:
3-(3-fluorobenzyl)pyrrolidine is utilized as a building block in the synthesis of pharmaceuticals, contributing to the development of new drugs and organic compounds. Its unique structure allows for the creation of a variety of chemical entities with potential therapeutic applications.
Used in Medicinal Chemistry and Drug Discovery:
3-(3-fluorobenzyl)pyrrolidine is employed as a component in medicinal chemistry and drug discovery processes. Its structural and chemical properties may offer advantages in the design and synthesis of new compounds with biological activity. However, its specific biological and pharmacological activities are not yet fully understood, necessitating further research to explore its potential uses in this field.
While the specific applications of 3-(3-fluorobenzyl)pyrrolidine in different industries are not explicitly detailed in the provided materials, its primary role in research and development for pharmaceutical synthesis and its potential in medicinal chemistry and drug discovery highlight its importance in the scientific community. Further studies are required to elucidate its full range of applications and to harness its properties for the advancement of medical treatments and chemical innovations.

Upstream product

• 1000198-84-4 1-Benzyl-3-(3-fluoro-benzyl)-pyrrolidine 
• 138108-72-2 tert-butyl (R)-3-hydroxymethylpyrrolidine-1-carboxylate 
• 768-35-4 3-fluorophenylboronic acid 
• 1187932-69-9 (R)-tert-butyl 3-(iodomethyl)pyrrolidine-1-carboxylate 
• 1412977-28-6 tert butyl (R)-3-(3-fluorobenzyl)-pyrrolidine-1-carboxylate 

Downstream Products

• 1412974-73-2 (1aRS,7bSR)-5-[2-((R)-1-ethylpyrrolidin-3-ylmethyl)-4-fluombenzenesulfonyl-amino]-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-4-catboxylic acid 
• 1412974-73-2 (1aRS,7bSR)-5-[2-((R)-1-ethylpyrrolidin-3-ylmethyl)-4-fluorobenzenesulfonyl-amino]-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-4-carboxylic acid 
• 1609034-44-7 methyl (1aRS,7bSR)-5-[2-((R)-1-ethylpyrrolidin-3-ylmethyl)-4-fluorobenzenesulfonyl-amino]-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-4-carboxylate 
• 1412974-75-4 (1aR,7bS)-5-[2-((R)-1-ethylpyrrolidin-3-ylmethyl)-4-fluorobenzenesulfonyl-amino]-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-4-carboxylic acid 

Relevant articles and documents

METHODS OF TREATING LIVER DISEASES

The invention provides tricyclic compounds and their use in treating liver disorders, such as non-alcoholic steatohepatitis and related disorders (e.g., fibrosis). The compounds are contemplated to have activity against methionyl aminopeptidase 2.

PARTIALLY SATURATED TRICYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME

The invention provides tricyclic compounds and their use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making various tricyclic compounds are provided. The compounds are contemplated to have activity against methionyl aminopeptidase 2.

Substituted phenyl methanone derivatives

The present invention relates to compounds of formula I wherein R1, R2, R3, X, n, and m are as defined herein and to pharmaceutically acceptable acid addition salts thereof, to pharmaceutical compositions containing them,