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1003560-58-4

1-BOC-3-(4-FLUOROPHENYL)-3-HYDROXYPYRROLIDINE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1003560-58-4 Structure

  • Basic information

    1. Product Name: 1-BOC-3-(4-FLUOROPHENYL)-3-HYDROXYPYRROLIDINE
    2. Synonyms: 1-BOC-3-(4-FLUOROPHENYL)-3-HYDROXYPYRROLIDINE;tert-butyl 3-(4-fluorophenyl)-3-hydroxypyrrolidine-1-carboxylate
    3. CAS NO:1003560-58-4
    4. Molecular Formula: C15H20FNO3
    5. Molecular Weight: 281.3226032
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1003560-58-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-BOC-3-(4-FLUOROPHENYL)-3-HYDROXYPYRROLIDINE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-BOC-3-(4-FLUOROPHENYL)-3-HYDROXYPYRROLIDINE(1003560-58-4)
    11. EPA Substance Registry System: 1-BOC-3-(4-FLUOROPHENYL)-3-HYDROXYPYRROLIDINE(1003560-58-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1003560-58-4(Hazardous Substances Data)

1003560-58-4 Usage

Type of compound

Pyrrolidine derivative

Protecting group

tert-butoxycarbonyl (BOC) attached to the nitrogen atom

Functional groups

a. Hydroxy group attached to the pyrrolidine ring
b. Fluorophenyl substituent attached to the third carbon atom

Applications

a. Organic synthesis
b. Medicinal chemistry
c. Building block for the synthesis of biologically active molecules

Potential uses

a. Fluorescent probe in biological studies due to the presence of the fluorophenyl group

Check Digit Verification of cas no

The CAS Registry Mumber 1003560-58-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,3,5,6 and 0 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1003560-58:
(9*1)+(8*0)+(7*0)+(6*3)+(5*5)+(4*6)+(3*0)+(2*5)+(1*8)=94
94 % 10 = 4
So 1003560-58-4 is a valid CAS Registry Number.

1003560-58-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-Butyl 3-(4-fluorophenyl)-3-hydroxypyrrolidine-1-carboxylate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1003560-58-4 SDS

1003560-58-4Relevant articles and documents

Oxidative Deconstruction of Azetidinols to α-Amino Ketones

Allen, Lewis A. T.,Natho, Philipp,Parsons, Philip J.,Raclea, Robert-Cristian,White, Andrew J. P.

, p. 9375 - 9385 (2020/08/14)

A silver-mediated synthesis of α-amino ketones via the oxidative deconstruction of azetidinols has been developed using a readily scalable protocol with isolated yields up to 80percent. The azetidinols are easily synthesized in one step and can act as protecting groups for these pharmaceutically relevant synthons. Furthermore, mechanistic insights are presented and these data have revealed that the transformation is likely to proceed through the β-scission of an alkoxy radical, followed by oxidation and C-N cleavage of the resulting α-amido radical.

SUBSTITUTED AZOLE AROMATIC HETEROCYCLES AS INHIBITORS OF 11BETA-HSD-1

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Page/Page column 96, (2008/06/13)

Compounds of formula I and IV are described and have therapeutic utility, particularly in the treatment of diabetes, obesity and related conditions and disorder: wherein the variables A-B, R1, R2, m, and Q are described herein.

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