101221-54-9 Usage
Ethanol derivative
2-[1-(1H-indol-1-yl)ethoxy]ethanol is derived from ethanol, which means it has a hydroxyl (-OH) group attached to an aliphatic carbon chain.
Indole group
2-[1-(1H-indol-1-yl)ethoxy]ethanol contains an indole group, which is a bicyclic heterocyclic compound consisting of a six-membered aromatic ring fused to a five-membered nitrogen-containing ring.
Organic synthesis
2-[1-(1H-indol-1-yl)ethoxy]ethanol is commonly used in organic synthesis, which is the process of constructing complex organic molecules from simpler precursors.
Pharmaceutical research
2-[1-(1H-indol-1-yl)ethoxy]ethanol is also used in pharmaceutical research, as it may have potential applications in the development of new drugs.
Biochemical tool
2-[1-(1H-indol-1-yl)ethoxy]ethanol can be used as a biochemical tool, which means it can be used to study biological processes or to manipulate biological systems.
Health risks
It is important to handle this chemical with caution as it may pose health risks if not properly handled. It is not specified what the exact risks are, but it is important to follow proper safety protocols when working with 2-[1-(1H-indol-1-yl)ethoxy]ethanol.
Check Digit Verification of cas no
The CAS Registry Mumber 101221-54-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,1,2,2 and 1 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 101221-54:
(8*1)+(7*0)+(6*1)+(5*2)+(4*2)+(3*1)+(2*5)+(1*4)=49
49 % 10 = 9
So 101221-54-9 is a valid CAS Registry Number.
101221-54-9Relevant articles and documents
Hydroxyalkylation of indole with cyclic carbonates catalyzed by ionic liquids
Gao, Guohua,Zhang, Lifeng,Wang, Binshen
, p. 1187 - 1191 (2013)
A simple and eco-friendly procedure has been developed for the synthesis of hydroxyalkyl indoles from indole and cyclic carbonates in the presence of a catalytic amount of imidazolium based ionic liquids under solvent-free conditions. The effects of reaction time, the catalyst amount, temperature, and the ratio of the reactants were investigated to develop the optimum conditions for the transformation. Under the optimized reaction conditions, indole reacted with ethylene carbonate or propylene carbonate to give 1-(2-hydroxyethyl)indole or 1-(2-hydroxypropyl)indole, as well as the corresponding sequential derivatives, in high yields. The catalytic activity of the ionic liquids was affected by the anions of the ionic liquids in the order of BF4 - - - -, which was consistent with the hydrogen bond basicity of the anions of the ionic liquids.
HETEROCYCLIC COMPOUNDS AS INHIBITORS OF LEUKOTRIENE PRODUCTION
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Paragraph 0168; 0169, (2013/08/14)
The present invention relates to compound of formula (I): or pharmaceutically acceptable salts thereof, wherein R1-R7, A and HET are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes
