NOVEL ANNULATION REACTIONS : THE DIRECT SYNTHESIS OF CYCLOPENTANES USING A LEWIS ACID ACTIVATED BISFUNCTIONAL ANNULATING REAGENT
In a novel one-pot reaction 3,3-Dimethoxy-1-trimethylstannyl-propane (1) reacts in the presence of Lewis acids with O-silylated enolates in a annulation to form fused cyclopentanes possessing a bridgehead hydroxy group.