103026-02-4

Basic information

• Product Name: 2-AMINO-1-(2-FURYLMETHYL)-4,5-DIMETHYL-1H-PYRROLE-3-CARBONITRILE
• Synonyms: 2-AMino-1-(furan-2-ylMethyl)-4,5-diMethyl-1H-pyrrole-3-carbonitrile;1H-Pyrrole-3-carbonitrile,2-aMino-1-(2-furanylMethyl)-4,5-diMethyl-;2-amino-1-(furan-2-ylmethyl)-4,5-dimethylpyrrole-3-carbonitrile
• CAS NO: 103026-02-4
• Molecular Formula: C₁₂H₁₃N₃O
• Molecular Weight: 0
• Mol File: 103026-02-4.mol

Chemical Properties

• Boiling Point: 414.5°Cat760mmHg
• Flash Point: 204.5°C
• Appearance: /
• Density: 1.21g/cm³
• Vapor Pressure: 4.44E-07mmHg at 25°C
• Refractive Index: 1.608
• CAS DataBase Reference: 2-AMINO-1-(2-FURYLMETHYL)-4,5-DIMETHYL-1H-PYRROLE-3-CARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-1-(2-FURYLMETHYL)-4,5-DIMETHYL-1H-PYRROLE-3-CARBONITRILE(103026-02-4)
• EPA Substance Registry System: 2-AMINO-1-(2-FURYLMETHYL)-4,5-DIMETHYL-1H-PYRROLE-3-CARBONITRILE(103026-02-4)

Safety Data

• Hazardous Substances Data: 103026-02-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-AMINO-1-(2-FURYLMETHYL)-4,5-DIMETHYL-1H-PYRROLE-3-CARBONITRILE is used as a potential drug or pharmaceutical intermediate due to its studied biological activities. Its unique structure and properties make it a candidate for further research and development in the creation of new medications or as a component in existing ones.
Used in Research and Development:
In the field of scientific research, 2-AMINO-1-(2-FURYLMETHYL)-4,5-DIMETHYL-1H-PYRROLE-3-CARBONITRILE serves as a subject for exploration into its biological activities and potential applications. Researchers utilize 2-AMINO-1-(2-FURYLMETHYL)-4,5-DIMETHYL-1H-PYRROLE-3-CARBONITRILE to study its interactions with biological systems and to understand its mechanisms of action, which can contribute to the advancement of medical and pharmaceutical sciences.

InChI:InChI=1/C12H13N3O/c1-8-9(2)15(12(14)11(8)6-13)7-10-4-3-5-16-10/h3-5H,7,14H2,1-2H3

Upstream product

• 109-77-3 malononitrile 
• 617-89-0 furan-2-ylmethanamine 
• 513-86-0 3-hydroxy-2-butanon 

Downstream Products

• 103026-12-6 7-(2-Furanylmethyl)-5,6-dimethyl-7H-pyrrolo<2,3-d>pyrimidin-4-amin 
• 103026-14-8 4-Chlor-7-(2-furanylmethyl)-5,6-dimethyl-7H-pyrrolo(2,3-d)pyrimidin 
• 82703-35-3 5,6-Dimethyl-7H-pyrrolo<2,3-d>pyrimidin-4(3H)-on 

Relevant articles and documents

Synthesis and rearrangements of 7H-pyrrolo[3,2-e][1,2,4]triazolo[1,5-c]-and 7h-pyrrolo[3,2-e][1,2,4]triazolo[4,3-c]pyrimidines

7H-Pyrrolo[3,2-e][1,2,4]triazolo[1,5-c]pyrimidines were synthesized by the reactions of 2-ethoxymethyleneamino-1H-pyrrole-3-carbonitriles with acid hydrazides and by the reactions of aminoiminopyrimidines (prepared based on the above-mentioned carbonitriles) with acid chlorides.

Synthesis of 7-Unsubstituted 7H-Pyrrolopyrimidines

The title compounds 4 are obtained by N-7 dealkylation of the 2-furanylmethyl, 2-thiophenylmethyl, or 1-phenylethyl group from 2a-g and 10 a-j with polyphosphoric acid.In contrast to the 2-furanylmethyl group the 2-thiophenylmethyl and 1-phenylethyl group