103420-82-2

Basic information

• Product Name: 1H-INDOLE-2-CARBOXYLIC ACID ((R)-1-METHYL-2-OXO-5-PHENYL-2,3-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-3-YL)-AMIDE
• Synonyms: 1H-INDOLE-2-CARBOXYLIC ACID ((R)-1-METHYL-2-OXO-5-PHENYL-2,3-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-3-YL)-AMIDE
• CAS NO: 103420-82-2
• Molecular Formula: C₂₅H₂₀N₄O₂
• Molecular Weight: 408.4519
• Mol File: 103420-82-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-INDOLE-2-CARBOXYLIC ACID ((R)-1-METHYL-2-OXO-5-PHENYL-2,3-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-3-YL)-AMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-INDOLE-2-CARBOXYLIC ACID ((R)-1-METHYL-2-OXO-5-PHENYL-2,3-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-3-YL)-AMIDE(103420-82-2)
• EPA Substance Registry System: 1H-INDOLE-2-CARBOXYLIC ACID ((R)-1-METHYL-2-OXO-5-PHENYL-2,3-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-3-YL)-AMIDE(103420-82-2)

Safety Data

• Hazardous Substances Data: 103420-82-2(Hazardous Substances Data)

Upstream product

• 58881-45-1 Indole-2-carbonyl chloride 
• 103343-65-3 (3R)-3-amino-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one 
• 1477-50-5 Indole-2-carboxylic acid 
• 161365-74-8 benzyl N-[[(2-benzoylphenyl)carbamoyl](1H-1,2,3-benzotriazol-1-yl)methyl]carbamate 
• 161365-75-9 1,3-Dihydro-1-methyl-5-phenyl-3(S)-<<(R)-α-methylbenzyloxycarbonyl>amino>-2H-1,4-benzodiazepin-2-one 
• 161443-31-8 1,3-Dihydro-5-phenyl-3(S)-<<(R)-α-methylbenzyloxycarbonyl>amino>-2H-1,4-benzodiazepin-2-one 
• 103343-47-1 3-amino-5-phenyl-1,3-dihydrobenzo[e][1,4]diazepin-2-one 
• 108895-97-2 2-α-(benzyloxycarbonyl)glycinyl)amino>benzophenone 
• 108895-98-3 benzyl 2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylcarbamate 

Relevant articles and documents

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3-(Acylamino)-5-phenyl-2H-1,4-benzodiazepines, antagonists of the peptide hormone cholecystokinin (CCK), are described.Developed by reasoned modification of the known anxiolytic benzodiazepines, these compounds provide highly potent, orally effective ligands selective for peripheral (CCK-A) receptors, with binding affinities approaching or equaling that of the natural ligand CCK-8.The distinction between CCK-A receptors on the one hand and CNS (CCK-B), gastrin, and central benzodiazepine receptors on the other is demonstrated by using the structure-activity profiles of the new compounds.Details of the binding of these agents to CCK-A receptors are examined, and the method of development of these compounds is discussed in terms of its relevance to the general problem of drug discovery.