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1H-Indazole-4-carboxylic acid, 5-bromo-, methyl ester is a chemical compound characterized by the molecular formula C9H7BrN2O2. It is a methyl ester derivative of 1H-Indazole-4-carboxylic acid, which is recognized for its potential pharmaceutical and biochemical applications. The incorporation of a bromine atom in its structure endows it with unique reactivity and properties, making it a versatile compound for various chemical reactions and studies. 1H-Indazole-4-carboxylic acid, 5-bromo-, methyl ester holds promise in the realms of medicinal chemistry and the synthesis of other organic compounds, positioning it as a valuable asset in pharmaceutical and biochemical research.

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  • 1037840-79-1 Structure
  • Basic information

    1. Product Name: 1H-Indazole-4-carboxylic acid, 5-broMo-, Methyl ester
    2. Synonyms: 1H-Indazole-4-carboxylic acid, 5-broMo-, Methyl ester;Methyl 5-bromo-1H-indazole-4-carboxylate;5-Bromo-1h-indazole-4-carboxylic acid,methyl ester
    3. CAS NO:1037840-79-1
    4. Molecular Formula: C9H7BrN2O2
    5. Molecular Weight: 255.06808
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1037840-79-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 391.9±22.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.709±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. PKA: 11.17±0.40(Predicted)
    10. CAS DataBase Reference: 1H-Indazole-4-carboxylic acid, 5-broMo-, Methyl ester(CAS DataBase Reference)
    11. NIST Chemistry Reference: 1H-Indazole-4-carboxylic acid, 5-broMo-, Methyl ester(1037840-79-1)
    12. EPA Substance Registry System: 1H-Indazole-4-carboxylic acid, 5-broMo-, Methyl ester(1037840-79-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1037840-79-1(Hazardous Substances Data)

1037840-79-1 Usage

Uses

Used in Pharmaceutical Industry:
1H-Indazole-4-carboxylic acid, 5-bromo-, methyl ester is utilized as a key intermediate in the synthesis of pharmaceutical compounds for its unique reactivity and structural properties. The presence of the bromine atom allows for further functionalization and modification, which can be crucial in the development of new drugs with specific therapeutic targets.
Used in Biochemical Research:
In the field of biochemical research, 1H-Indazole-4-carboxylic acid, 5-bromo-, methyl ester serves as a valuable tool for studying the interactions and mechanisms of various biological systems. Its unique structure can be employed to probe and understand complex biochemical processes, potentially leading to the discovery of novel therapeutic agents or insights into disease mechanisms.
Used in Organic Synthesis:
1H-Indazole-4-carboxylic acid, 5-bromo-, methyl ester is also used as a building block in organic synthesis, where its reactivity and properties can be harnessed to create a wide range of organic compounds. This versatility makes it an important compound in the development of new materials, agrochemicals, and other specialty chemicals.
Overall, 1H-Indazole-4-carboxylic acid, 5-bromo-, methyl ester is a multifaceted chemical compound with a broad spectrum of applications across various industries, particularly in pharmaceutical and biochemical research, where its unique properties and reactivity contribute to the advancement of scientific knowledge and the development of innovative solutions.

Check Digit Verification of cas no

The CAS Registry Mumber 1037840-79-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,7,8,4 and 0 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1037840-79:
(9*1)+(8*0)+(7*3)+(6*7)+(5*8)+(4*4)+(3*0)+(2*7)+(1*9)=151
151 % 10 = 1
So 1037840-79-1 is a valid CAS Registry Number.

1037840-79-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Methyl 5-bromo-1H-indazole-4-carboxylate

1.2 Other means of identification

Product number -
Other names 5-Bromo-1H-indazole-4-carboxylic acid methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1037840-79-1 SDS

1037840-79-1Downstream Products

1037840-79-1Relevant articles and documents

Discovery of a Potent and Orally Bioavailable Melatonin Receptor Agonist

Hoashi, Yasutaka,Takai, Takafumi,Kosugi, Yohei,Nakashima, Masato,Nakayama, Masaharu,Hirai, Keisuke,Uchikawa, Osamu,Koike, Tatsuki

, p. 3059 - 3074 (2021/04/06)

To develop potent and orally bioavailable melatonin receptor (MT1 and MT2) agonists, a novel series of 5-6-5 tricyclic derivatives was designed, synthesized, and evaluated. The synthesized indeno[5,4-d][1,3]oxazole, cyclopenta[c]pyrazolo[1,5-a]pyridine, i

HETEROCYCLIC COMPOUND

-

, (2020/06/23)

Provided is a heterocyclic compound that can have an antagonistic action on an NMDA receptor containing the NR2B subunit, and is expected to be useful as a prophylactic or therapeutic agent for major depression, bipolar disorder, migraine, pain, periphera

BICYCLIC COMPOUND AND PHARMACEUTICAL USE THEREOF

-

Page/Page column 80, (2010/01/29)

The present invention provides a compound represented by the formula wherein R1 is a hydrocarbon group optionally having substituent(s), amino optionally having substituent(s), hydroxy optionally having a substituent or a heterocyclic group optionally having substituent(s); R2 is a hydrogen atom or a hydrocarbon group optionally having substituent(s); Xa and Xb are each C, N, O or S; Xc and Xd are each C or N; m is 0-2; n is 1-3; ring A is a 5-membered ring optionally having substituent(s); ring B is a 6-membered ring optionally having substituent(s); and ring C is a 3- to 5-membered ring optionally having substituent(s), provided that when Xa, Xc and Xd are each C, then Xb is N or S, or a salt thereof, which is useful as an agent for the prophylaxis or treatment of a disease relating to an action of melatonin, and the like.

TRICYCLIC COMPOUND AND PHARMACEUTICAL USE THEREOF

-

Page/Page column 42, (2009/09/26)

The present invention provides a compound represented by the formula wherein R1 is a hydrocarbon group optionally having substituent(s), amino optionally having substituent(s), hydroxy optionally having a substituent or a heterocyclic group opt

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