103877-51-6

Basic information

• Product Name: ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxo-quinoline-3-carboxylate
• Synonyms: 7-Chloro-1-cyclopropyl-8-methyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid ethyl ester
• CAS NO: 103877-51-6
• Molecular Formula: C₁₆H₁₆ClNO₃
• Molecular Weight: 305.76
• EINECS: 600-496-4
• Mol File: 103877-51-6.mol

Chemical Properties

• Boiling Point: 448.7°C at 760 mmHg
• Flash Point: 225.2°C
• Density: 1.362g/cm³
• Vapor Pressure: 3.04E-08mmHg at 25°C
• Refractive Index: 1.62
• PKA: -3.24±0.40(Predicted)
• CAS DataBase Reference: ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxo-quinoline-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxo-quinoline-3-carboxylate(103877-51-6)
• EPA Substance Registry System: ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxo-quinoline-3-carboxylate(103877-51-6)

Safety Data

• Hazardous Substances Data: 103877-51-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxo-quinoline-3-carboxylate is used as a pharmaceutical intermediate for the synthesis of various drugs. Its unique structure allows it to serve as a building block in the development of new medications, particularly those targeting specific biological pathways or receptors.
As a pharmaceutical intermediate, ethyl 7-chloro-1-cyclopropyl-8-methyl-4-oxo-quinoline-3-carboxylate is utilized for the following reasons:
1. Its heterocyclic structure can be modified to create a variety of drug candidates with different biological activities.
2. The presence of functional groups, such as the chlorine atom and the cyclopropyl group, enables further chemical reactions to produce more complex molecules with specific therapeutic properties.
3. The compound's structural diversity makes it a valuable asset in the design and synthesis of novel drugs, potentially leading to the discovery of new treatments for various diseases and conditions.

Upstream product

• 924-99-2 ethyl 3-(dimethylamino)acrylate 
• 83277-23-0 2,4-Dichloro-3-methyl-benzoic acid 
• 103877-38-9 ethyl 3-(cyclopropylamino)-2-(2,4-dichloro-3-methylbenzoyl)acrylate 
• 157652-32-9 1-(2,4-dichloro-3-methylphenyl)ethanone 
• 118-69-4 2,6-dichlorotoluene 

Downstream Products

• 446299-90-7 C₃₀H₂₉N₃O₄ 
• 245765-41-7 ozenoxacin 

Relevant articles and documents

CRYSTALLINE FORM OF OZENOXACIN AND PROCESSES FOR PREPARATION THEREOF

The present invention relates to a crystalline form of 1-cyclopropyl-8-methyl-7- (5-methyl-6-(methylamino)pyridin-3-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid the compound of formula-1, which is represented by the following structural formula-1. The

Preparation method of Ozenoxacin and intermediates thereof

The invention provides compounds represented by the formula (IIIb) and a preparation method thereof. The invention also provides an application of the compound represented by the formula (IIIb) as a key intermediate in Ozenoxacin preparation.