103986-76-1

Basic information

• Product Name: (2E)-3-(2-METHOXY-5-METHYLPHENYL)ACRYLIC ACID
• Synonyms: Cinnamicacid, 2-methoxy-5-methyl- (6CI); 2-Methoxy-5-methylcinnamic acid;3-(2-Methoxy-5-[methyl]phenyl)acrylic acid
• CAS NO: 103986-76-1
• Molecular Formula: C₁₁H₁₂O₃
• Molecular Weight: 192.21
• Mol File: 103986-76-1.mol

Chemical Properties

• Boiling Point: 339.6°Cat760mmHg
• Flash Point: 132.8°C
• Appearance: /
• Density: 1.162g/cm³
• Vapor Pressure: 3.53E-05mmHg at 25°C
• CAS DataBase Reference: (2E)-3-(2-METHOXY-5-METHYLPHENYL)ACRYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-3-(2-METHOXY-5-METHYLPHENYL)ACRYLIC ACID(103986-76-1)
• EPA Substance Registry System: (2E)-3-(2-METHOXY-5-METHYLPHENYL)ACRYLIC ACID(103986-76-1)

Safety Data

• Hazardous Substances Data: 103986-76-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
(2E)-3-(2-METHOXY-5-METHYLPHENYL)ACRYLIC ACID is used as a building block in the synthesis of various organic compounds for pharmaceutical research. Its potential biological activities make it a promising candidate for the development of pharmaceutical drugs.
Used in Organic Synthesis:
(2E)-3-(2-METHOXY-5-METHYLPHENYL)ACRYLIC ACID is used as a key intermediate in the synthesis of various organic compounds, contributing to the development of new chemical entities.
Used in Medicinal Applications:
(2E)-3-(2-METHOXY-5-METHYLPHENYL)ACRYLIC ACID is used as a potential therapeutic agent due to its reported antioxidant and anti-inflammatory properties, which can be beneficial in the treatment of various medical conditions.
Used in Cosmetic Applications:
(2E)-3-(2-METHOXY-5-METHYLPHENYL)ACRYLIC ACID is used in the development of cosmetic products, leveraging its antioxidant and anti-inflammatory properties to provide skincare benefits.

InChI:InChI=1/C11H12O3/c1-8-3-5-10(14-2)9(7-8)4-6-11(12)13/h3-7H,1-2H3,(H,12,13)/p-1/b6-4+

Upstream product

• 1194827-68-3 ethyl (E)-3-(2-methoxy-5-methylphenyl)acrylate 
• 7083-19-4 2-methoxy-5-methylbenzaldehyde 
• 22002-45-5 2-bromo-4-methylanisole 
• 141-82-2 malonic acid 
• 108-24-7 acetic anhydride 
• 858786-32-0 3-hydroxy-3-(2-methoxy-5-methyl-phenyl)-propionic acid ethyl ester 
• 92-48-8 6-methylcoumarin 
• 77-78-1 dimethyl sulfate 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 107274-42-0 2-methoxy-5-methyl-cinnamic acid ethyl ester 

Downstream Products

• 61371-44-6 3-(2'-methoxy-5-methylphenyl)propanoic acid 
• 124937-55-9 4-(2-Methoxy-5-methylphenyl)-6-methyl-3,4-dihydrocoumarin 
• 857288-55-2 (S)-3-(2-methoxy-5-methylphenyl)-3-phenylpropanal 
• 889135-71-1 (E)-3-(2-methoxy-5-methylphenyl)acrylaldehyde 

Relevant articles and documents

TETRAHYDROBENZOTHIOPHENE DERIVATIVES

Compounds of a certain formula I, in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity.

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Two different high yielding synthetic routes both starting with 6-methylcoumarin 2 have been described to prepare 4-hydroxy-7-methyl-1-indanone 1, a constituent of cyanobacterium Nostoc commune having antibacterial activity. In the first route, methylative lactone ring opening of the coumarin 2 followed by catalytic hydrogenation of the cinnamyl double bond and subsequent PPA cyclization gives the methyl ether 5 of 1 which on demethylation gives 1 in excellent yield. Alternatively, catalytic hydrogenation of 2 followed by fusion with anhydrous AlCl3 gives high yield of 1 in just two steps.

NTETRAHYDROPYRIDOTHIOPHENE DERIVATIVES FOR THE TREATMENT OF CANCER

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