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2-bromo-3-methoxybenzaldehyde, an organic compound with the molecular formula C8H7BrO2, is a pale yellow solid characterized by a strong, sweet, and floral odor. It serves as a crucial building block in the synthesis of pharmaceuticals, agrochemicals, and organic materials, playing a significant role in the field of organic chemistry.

10401-18-0

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10401-18-0 Usage

Uses

Used in Pharmaceutical Industry:
2-bromo-3-methoxybenzaldehyde is used as a key intermediate in the synthesis of various pharmaceutical products. Its unique chemical structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-bromo-3-methoxybenzaldehyde is utilized as a precursor in the production of agrochemicals, contributing to the development of innovative and effective solutions for crop protection and pest management.
Used in Organic Material Production:
2-broMo-3-Methoxybenzaldehyde is also employed in the creation of organic materials, where its properties can be harnessed to produce materials with specific characteristics, such as improved stability or enhanced performance in various applications.
Used in Research and Manufacturing Processes:
2-bromo-3-methoxybenzaldehyde is an important tool in research and manufacturing, enabling the development of new chemical processes and the synthesis of novel compounds with potential applications in various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 10401-18-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,4,0 and 1 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 10401-18:
(7*1)+(6*0)+(5*4)+(4*0)+(3*1)+(2*1)+(1*8)=40
40 % 10 = 0
So 10401-18-0 is a valid CAS Registry Number.

10401-18-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Bromo-3-methoxybenzaldehyde

1.2 Other means of identification

Product number -
Other names 2-bromo-3-methoxy-benzaldehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10401-18-0 SDS

10401-18-0Relevant articles and documents

Structure Guided Design, Synthesis, and Biological Evaluation of Novel Benzosuberene Analogues as Inhibitors of Tubulin Polymerization

Niu, Haichan,Strecker, Tracy E.,Gerberich, Jeni L.,Campbell, James W.,Saha, Debabrata,Mondal, Deboprosad,Hamel, Ernest,Chaplin, David J.,Mason, Ralph P.,Trawick, Mary Lynn,Pinney, Kevin G.

, p. 5594 - 5615 (2019)

A promising design paradigm for small-molecule inhibitors of tubulin polymerization that bind to the colchicine site draws structural inspiration from the natural products colchicine and combretastatin A-4 (CA4). Our previous studies with benzocycloalkeny

Efficient Enantioselective Syntheses of (+)-Dalesconol A and B

Zhao, Guoqing,Xu, Guangqing,Qian, Chao,Tang, Wenjun

, p. 3360 - 3363 (2017)

We herein report the first enantioselective syntheses of immunosuppressants (+)-dalesconol A and B in a highly efficient and concise manner, which features an efficient palladium-catalyzed enantioselective dearomative cyclization-kinetic resolution cascade to install the chiral all-carbon quaternary center, an effective sterically hindered Stille coupling, a powerful 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) oxidation to furnish all requisite unsaturation, and a tandem hydrolysis-ring closure sequence.

Synthesis and structure–activity relationships of aristoyagonine derivatives as brd4 bromodomain inhibitors with x-ray co-crystal research

Jung, Kwan-Young,Kim, Yeongrin,Lee, Byung Il,Lee, Joo-Youn,Lee, Kyu Myung,Park, Chi Hoon,Park, Tae Hyun,Ryu, Seong Eon,Yoo, Minjin,Yoo, Miyoun

, (2021/06/16)

Epigenetic regulation is known to play a key role in progression of anti-cancer therapeutics. Lysine acetylation is an important mechanism in controlling gene expression. There has been increasing interest in bromodomain owing to its ability to modulate t

BENZOSUBERENE ANALOGUES AND RELATED COMPOUNDS WITH ACTIVITY AS ANTICANCER AGENTS

-

Paragraph 0063, (2020/03/01)

A series of benzosuberene analogues demonstrate effective inhibition of tubulin polymerization, cytotoxicity against human cancer cell lines, and vascular disruption in tumors.

BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS

-

Paragraph 1413-1414, (2018/06/29)

This invention is directed to benzenesulfonamide compounds, as stereoisomers, enantiomers, tautomers thereof or mixtures thereof; or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment of diseases or conditions associated with voltage-gated sodium channels, such as epilepsy and/or epileptic seizure disorders.

Exploration of Biaryl Carboxylic Acids as Proton Shuttles for the Selective Functionalization of Indole C-H Bonds

Pi, Jing-Jing,Lu, Xiao-Yu,Liu, Jing-Hui,Lu, Xi,Xiao, Bin,Fu, Yao,Guimond, Nicolas

, p. 5791 - 5800 (2018/05/14)

A survey of diversely substituted 2-arylbenzoic acids were synthesized and tested for use as proton shuttle in the direct arylation of indoles with bromobenzenes. It was found that 3-ethoxy-2-phenylbenzoic acid gives superior yield and selectivity for this class of substrates.

COMPOUNDS FOR THE INHIBITION OF INDOLEAMINE-2,3-DIOXYGENASE

-

Paragraph 0586-0587, (2016/04/09)

The present invention relates to compounds, and pharmaceutically acceptable compositions thereof, useful as antagonists of IDO, and for the treatment of IDO-related disorders.

Design of living ring-opening alkyne metathesis

Fischer, Felix R.,Nuckolls, Colin

supporting information; experimental part, p. 7257 - 7260 (2010/11/05)

It's alive: A ring-strained alkyne based on dibenzo[a,e][8]annulene undergoes ringopening metathesis polymerization (ROMP) to give a high-molecular-weight poly(ortho-phenylene) featuring alternating ethyl and ethynyl linkers along the polymer backbone. The molybdenumalkylidyne- based catalyst system discriminates between strained and unstrained alkynes to yield a living polymer with an unparalleled low polydispersity.

Chiral oxazoline route to enantiomerically pure biphenyls: Magnesio and copper mediated asymmetric hetero- and homo-coupling reactions

Meyers,Nelson, Todd D.,Moorlag, Henk,Rawson, David J.,Meier, Anton

, p. 4459 - 4473 (2007/10/03)

A series of chiral biphenyls were prepared via asymmetric reactions involving chiral oxazolines. One series of chiral biphenyls was reached by the magnesium mediated coupling of aryl bromides (via their Grignard reagents) with o-methoxyaryl oxazolines. In

An asymmetric synthesis of a C2 symmetric tetrasubstituted biaryl: 2,2′-Dihydroxy-6,6′-dimethyl-1,1′-biphenyl, a stable chiral system

Moorlag, Henk,Meyers

, p. 6993 - 6996 (2007/10/02)

An asymmetric synthesis of enantiomerically pure bisphenol (S)-12 was accomplished in 40-50% by an oxazoline mediated biaryl coupling.

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