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4-CYANO-2-METHOXYBENZYL BROMIDE is a chemical compound characterized by the molecular formula C9H8BrNO. It is a benzyl bromide derivative featuring a cyano group and a methoxy group attached to the benzene ring. 4-CYANO-2-METHOXYBENZYL BROMIDE is recognized for its versatility in organic synthesis, serving as a key intermediate in the preparation of pharmaceuticals and agrochemicals. Its capacity to participate in substitution and elimination reactions makes it a valuable reagent for the synthesis of other organic compounds. Furthermore, 4-CYANO-2-METHOXYBENZYL BROMIDE has demonstrated potential biological activity and is under investigation for its pharmacological properties, positioning it as an important compound in the realm of organic chemistry.

104436-60-4

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104436-60-4 Usage

Uses

Used in Pharmaceutical Industry:
4-CYANO-2-METHOXYBENZYL BROMIDE is used as a synthetic intermediate for the development of various pharmaceuticals. Its unique structure allows for the creation of a wide range of medicinal compounds, contributing to the advancement of drug discovery and therapeutic options.
Used in Agrochemical Industry:
In the agrochemical sector, 4-CYANO-2-METHOXYBENZYL BROMIDE is utilized as a precursor in the synthesis of agrochemicals. Its role in formulating effective and targeted pest control agents is crucial for enhancing crop protection and agricultural productivity.
Used in Organic Synthesis:
4-CYANO-2-METHOXYBENZYL BROMIDE is employed as a reagent in organic synthesis, facilitating the formation of new organic compounds through substitution and elimination reactions. Its presence in these reactions is instrumental in the creation of complex organic molecules for various applications.
Used in Biological Research:
4-CYANO-2-METHOXYBENZYL BROMIDE is also used in biological research to explore its potential pharmacological properties. Studies on its biological activity are essential for understanding its role in medicine and potentially identifying new therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 104436-60-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,4,3 and 6 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 104436-60:
(8*1)+(7*0)+(6*4)+(5*4)+(4*3)+(3*6)+(2*6)+(1*0)=94
94 % 10 = 4
So 104436-60-4 is a valid CAS Registry Number.

104436-60-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(bromomethyl)-3-methoxybenzonitrile

1.2 Other means of identification

Product number -
Other names 4-CYANO-2-METHOXYBENZYL BROMIDE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:104436-60-4 SDS

104436-60-4Relevant articles and documents

ESTROGEN-RELATED RECEPTOR ALPHA (ERRα) MODULATORS

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Page/Page column 59, (2021/01/23)

The present invention is directed to compounds according to Formula (I) and the pharmaceutically acceptable salts thereof. The compounds can be used as modulators of Estrogen-related Receptor alpha (ERRα) and have utility in the treatment of ERRα-mediated

MASP-2 INHIBITORS AND METHODS OF USE

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Paragraph 1738-1740, (2019/12/24)

The present disclosure provides, inter alia, compounds with MASP-2 inhibitory activity, compositions of such compounds and methods of making and using such compounds.

Synthesis method of 2-methoxyl-4-cyanobenzaldehyde

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, (2018/04/03)

The invention discloses a synthesis method of 2-methoxyl-4-cyanobenzaldehyde. The method comprises the following steps: 1, carrying out acylating chlorination on 4-methyl-3-methoxybenzoic acid servingas a raw material, and then carrying out aminolysis to

HETEROCYCLIC CGRP RECEPTOR ANTAGONISTS

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Page/Page column 177-178, (2015/11/09)

The present invention is directed to heterocyclic compounds which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which CGRP is involved, such as migraine. The invention is also directed to pharmaceutical composi

ALDOSTERONE SYNTHASE AND/OR 11β-HYDROXYLASE INHIBITORS

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, (2008/06/13)

The present invention provides a compound of formula (I). Said compound is inhibitor of CYP11B2 and/or CYP11B1, and thus can be employed for the treatment of a disorder or disease mediated by CYP11B2 and/or CYP11B1.

Non-covalent thrombin inhibitors featuring P3-heterocycles with P1-monocyclic arginine surrogates

Reiner, John E.,Siev, Daniel V.,Araldi, Gian-Luca,Cui, Jingrong Jean,Ho, Jonathan Z.,Reddy, Komandla Malla,Mamedova, Lala,Vu, Phong H.,Lee, Kuen-Shan S.,Minami, Nathaniel K.,Gibson, Tony S.,Anderson, Susanne M.,Bradbury, Annette E.,Nolan, Thomas G.,Semple, J. Edward

, p. 1203 - 1208 (2007/10/03)

Investigations on P2-P3-heterocyclic dipeptide surrogates directed towards identification of an orally bioavailable thrombin inhibitor led us to pursue novel classes of achiral, non-covalent P1-arginine derivatives. The design, synthesis, and biological activity of inhibitors NC1-NC30 that feature three classes of monocyclic P1-arginine surrogates will be disclosed: (1) (hetero)aromatic amidines, amines and hydroxyamidines, (2) 2-aminopyrazines, and (3) 2-aminopyrimidines and 2-aminotetrahydropyrimidines.

Thrombin inhibitors, the preparation and use thereof

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, (2008/06/13)

Compounds of the formula and the salts thereof with physiologically tolerated acids and the stereoisomers thereof, in which the substituents have the meanings stated in the description, are described. Also disclosed are intermediates for their preparation. The compounds are suitable for controlling diseases.

A novel series of selective leukotriene antagonists: Exploration and optimization of the acidic region in 1,6-disubstituted indoles and indazoles

Yee,Bernstein,Adams,Brown,Cronk,Hebbel,Vacek,Krell,Snyder

, p. 2437 - 2451 (2007/10/02)

A systematic structure-activity exploration of the carboxylic acid region in a series of indole- or indazole-derived leukotriene antagonists 1 led to several discoveries. Use of the 3-methoxy-p-tolyl fragment (illustrated in acid 1) for connecting the indole and the acidic site provides the most potent carboxylic acids 1, tetrazoles 20, and aryl sulfonimides 21. The aryl sulfonimides are 5-500 times more potent (in vitro and/or in vivo) than the corresponding carboxylic acids 1. The o-tolyl sulfonimides such as 114 show greater oral potency than the phenyl sulfonimides at a given level of in vitro activity. Acidic keto sulfone derivatives 10 (Nu = CH(CO2CH3)SO2Ph) mimic the activity of the sulfonimides.

Heterocyclic amide derivatives and pharmaceutical use

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, (2008/06/13)

The invention concerns novel, pharmaceutically useful, amide derivatives of certain benzoheterocyclylalkanoic acids (and related tetrazoles and acylsulphonamides) of the formula I and salts thereof, wherein the radicals R1, R2, L, X, Y, Z, A1, Q, A2 and M have the meanings set out in the specification. The invention also includes pharmaceutical compositions incorporating a formula I compound or a salt thereof, a process for the manufacture of the said compound, together with intermediates for use in the latter process. STR1

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