104516-57-6

Basic information

• Product Name: 2-(5-ISOXAZOLYL)-4-METHYLPHENOL
• Synonyms: 2-(5-ISOXAZOLYL)-4-METHYLPHENOL;2-(ISOXAZOL-5-YL)-4-METHYLPHENOL;5-(2'-HYDROXY-5'-METHYLPHENYL)-ISOXAZOLE;5-(2Hydroxyl-5methylphenyl)-isoxazole
• CAS NO: 104516-57-6
• Molecular Formula: C₁₀H₉NO₂
• Molecular Weight: 175.18
• Mol File: 104516-57-6.mol

Chemical Properties

• Boiling Point: 319.5 °C at 760 mmHg
• Flash Point: 147 °C
• Appearance: /
• Density: 1.204 g/cm³
• CAS DataBase Reference: 2-(5-ISOXAZOLYL)-4-METHYLPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(5-ISOXAZOLYL)-4-METHYLPHENOL(104516-57-6)
• EPA Substance Registry System: 2-(5-ISOXAZOLYL)-4-METHYLPHENOL(104516-57-6)

Safety Data

• Hazardous Substances Data: 104516-57-6(Hazardous Substances Data)

Usage

Uses

Used in Veterinary Medicine:
2-(5-ISOXAZOLYL)-4-METHYLPHENOL is used as an anti-infective agent for treating infections caused by parasites in animals. It is particularly effective against protozoan parasites such as Giardia and helminths, which cause diseases like giardiasis and trichomoniasis. 2-(5-ISOXAZOLYL)-4-METHYLPHENOL's ability to target and eliminate these parasites makes it a valuable tool in the field of veterinary medicine.
Used in Antimicrobial Applications:
2-(5-ISOXAZOLYL)-4-METHYLPHENOL is used as an antimicrobial agent for its broad-spectrum activity against various microorganisms. Its efficacy in inhibiting the growth of protozoa and helminths highlights its potential use in treating infections caused by these organisms, both in humans and animals.
Used in Research and Development:
2-(5-ISOXAZOLYL)-4-METHYLPHENOL is used as a research compound for studying its potential applications in medicine. Its antimicrobial properties have been investigated for the treatment of tuberculosis, a disease caused by the bacterium Mycobacterium tuberculosis. Further research is needed to fully understand the compound's therapeutic potential and optimize its use in clinical settings.

Upstream product

• 89807-39-6 1-(2-hydroxy-5-methylphenyl)-3-(N,N-dimethylamino)propenone 
• 1450-72-2 5-methyl-2-hydroxyacetophenone 
• 89807-39-6 (2E)-3-(dimethylamino)-1-(2-hydroxy-5-methylphenyl)-2-propen-1-one 
• 38445-23-7 6-methyl-chromen-4-one 
• 90843-41-7 3-(2-hydroxy-5-methyl-phenyl)-3-oxo-propionaldehyde 
• 213689-90-8 (E)-3-Diethylamino-1-(2-hydroxy-5-methyl-phenyl)-propenone 

Downstream Products

• 164171-61-3 3-(2-hydroxy-5-methylphenyl)-3-oxopropanenitrile 

Relevant articles and documents

Zn(OTf)2-Catalyzed Formal [3 + 3] Cascade Annulation of Propargylic Alcohols with 2-Aminochromones: Accessing the Chromeno[2,3- b]pyridines

A Zn(OTf)2-catalyzed formal [3 + 3] cascade annulation strategy for the synthesis of functionalized chromeno[2,3-b]pyridines has been developed using propargylic alcohols and 2-aminochromones as the substrates. The protocol provides a convenien

Synthesis of 2,2′-diaminobischromones using a modified procedure for the rearrangement of 5-(2-hydroxyphenyl)isoxazole to 2-aminochromone

A modified procedure for the rearrangement of 5-(2-hydroxyphenyl)isoxazoles 6a-e to 2-aminochromones 8a-e was developed and this procedure was utilised in the synthesis of hitherto unreported bischromones 3a-c. The isoxazoles 6a-e were prepared regioselec

Synthesis of substituted isoxazoles and 1,3,4-oxadiazoles

A few novel 5-(2'-hydroxyaryl)-isoxazoles 3 and 2-(aryloxymethyl)-3-mercapto-1,3,4-oxadiazoles 8 have been synthesized from the intermediate enamino ketones 2, and tested for their herbicidal activity

Benzo-γ-pyrones. Part XV. Conversion of some 4-Oxo-4H-1-benzopyran-2-carboxylic Acids into 4H-1-Benzopyran-4-ones via Isoxazoles

The preparation of 5-substituted-3-isoxazolecarboxylic acids 2a-c and their transformation into the corresponding 2-aminochromones (5a-c) and 3-cyano-2-methylchromones (6a-c) is described. The structures of oximes of methylchromones were revised to isoxazoles 2d-f. The structures of the obtained compounds were proved by spectral methods (1H, 13C NMR, IR and MS). Key words: chromones, isoxazoles, NMR and MS spectra

The Reaction of S,S-Diphenylsulphilimine with Benzopyran-4-ones and Benzopyran-4-thiones

Benzopyran-4-ones unsubstituted at carbons 2 and 3 yield aziridines, amines and isoxazoles on treatment with diphenylsulphilimine.The product composition is temperature dependent, aziridines being the major products at room temperature and amines at highe