- COMPOUNDS
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A compound of formula (I), or a pharmaceutical salt thereof.
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Page/Page column 89-90
(2020/01/11)
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- 2 -AMINOQUINAZOLINE DERIVATIVES AND THEIR THERAPEUTIC USES
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A compound of formula (I) wherein X is NH2or OH and W is -C(O)-O- or -O-C(O)-; use thereof as a medicament, in particular for the treatment of inflammation, autoimmune disorder, immunogenic rejection reactions and cancer and for non-surgical abortion.
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Page/Page column 23
(2009/01/24)
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- Preparation of 3-cyano-4-fluorophenol
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The invention provides a process for the preparation of 4-fluorophenols of formula STR1 wherein n is 0 to 3, each R independently represents a halogen atom or an alkyl, alkoxy, cyano or optionally substituted amino group and Z represents a hydrogen or halogen atom or a cyano group characterized by reacting a fluorohalocyclohexadienone of formula STR2 wherein X represents a halogen atom, with a compound of formula A-Z, wherein Z is as defined above and A represents a hydrogen or alkali metal atom, provided that when both A and Z are hydrogen, the reaction is carried out in the additional presence of a Group VIII metal hydrogenation catalyst, and 4-fluorophenols of formula I per se wherein Z is a CN group.
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