104940-99-0

Basic information

• Product Name: 1-{1-[(2,4-dichlorophenyl)carbonyl]ethenyl}pyridin-2(1H)-one
• Synonyms: 1-[3-(2,4-dichlorophenyl)-3-oxoprop-1-en-2-yl]pyridin-2(1H)-one; 2(1H)-Pyridinone, 1-(1-(2,4-dichlorobenzoyl)ethenyl)-; 2(1H)-pyridinone, 1-[1-(2,4-dichlorobenzoyl)ethenyl]-
• CAS NO: 104940-99-0
• Molecular Formula: C₁₄H₉Cl₂NO₂
• Molecular Weight: 294.1328
• Mol File: 104940-99-0.mol

Chemical Properties

• Boiling Point: 499.9°C at 760 mmHg
• Flash Point: 256.1°C
• Density: 1.404g/cm³
• Vapor Pressure: 3.99E-10mmHg at 25°C
• Refractive Index: 1.625
• CAS DataBase Reference: 1-{1-[(2,4-dichlorophenyl)carbonyl]ethenyl}pyridin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{1-[(2,4-dichlorophenyl)carbonyl]ethenyl}pyridin-2(1H)-one(104940-99-0)
• EPA Substance Registry System: 1-{1-[(2,4-dichlorophenyl)carbonyl]ethenyl}pyridin-2(1H)-one(104940-99-0)

Safety Data

• Hazardous Substances Data: 104940-99-0(Hazardous Substances Data)

Upstream product

• 142-08-5 2-Pyridone 
• 2631-72-3 2,4-dichlorophenacyl bromide 
• 2234-16-4 1-(2,4-dichlorophenyl)ethan-1-one 

Relevant articles and documents

Synthesis and Antifungal Activity of a Series of Novel 1,2-Disubstituted Propenones

To find an antifungal agent other than those of the imidazole and triazole series, a new class of 1,2-disubstituted propenones I and II was prepared and tested for antifungal activity.Comparison of the structure-activity relationships showed that the conjugated structure of carbonyl and exomethylene groups in I and II plays an important role in potent antifungal acivity.However, it is noteworthy that compounds 53, 54, and 56, which have a hydroxymethyl or methoxymethyl group instead of an exo-methylene group in I, also showed potent activity.Although many compounds exhibited strong antifungal activity in vitro, none showed activity in vivo of oral efficacy against subacute systemic candidiasis in mice. '