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3-Chloro-4-hydroxybenzyl alcohol, also known as Saligenin hydrochloride, is a chemical compound that belongs to the class of organic compounds known as Phenylethanols. It features an aromatic ring with a hydroxyl group (-OH) and a benzyl alcohol group. 3-Chloro-4-hydroxybenzyl alchol is often identified by its CAS Registry Number, 1878-75-5. It is a relatively stable compound, but it is recommended to store it in cool, dry conditions in a well-sealed container to maintain its integrity. 3-Chloro-4-hydroxybenzyl alcohol is known for its potential applications in various fields, including the development of pharmaceuticals, agrochemicals, and dye intermediates. Due to its reactivity potential, common precautions should be taken when handling and storing this compound.

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  • 105960-29-0 Structure
  • Basic information

    1. Product Name: 3-Chloro-4-hydroxybenzyl alchol
    2. Synonyms: 3-Chloro-4-hydroxybenzyl alchol;BENZENEMETHANOL,3-CHLORO-4-HYDROXY;2-chloro-4-(hydroxymethyl)phenol
    3. CAS NO:105960-29-0
    4. Molecular Formula: C7H7ClO2
    5. Molecular Weight: 158.58228
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 105960-29-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 3-Chloro-4-hydroxybenzyl alchol(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-Chloro-4-hydroxybenzyl alchol(105960-29-0)
    11. EPA Substance Registry System: 3-Chloro-4-hydroxybenzyl alchol(105960-29-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 105960-29-0(Hazardous Substances Data)

105960-29-0 Usage

Uses

Used in Pharmaceutical Development:
3-Chloro-4-hydroxybenzyl alcohol is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the creation of a wide range of drug molecules, making it a valuable asset in the development of new medications.
Used in Agrochemical Production:
In the agrochemical industry, 3-Chloro-4-hydroxybenzyl alcohol is used as a starting material for the production of various agrochemicals. Its versatility in organic synthesis enables the creation of compounds that can be used in pest control, crop protection, and other agricultural applications.
Used in Dye Intermediates:
3-Chloro-4-hydroxybenzyl alcohol is also utilized in the production of dye intermediates. Its chemical properties make it suitable for the synthesis of dyes used in various industries, such as textiles, plastics, and printing inks. This application highlights the compound's potential in the chemical and materials science sectors.

Check Digit Verification of cas no

The CAS Registry Mumber 105960-29-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,9,6 and 0 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 105960-29:
(8*1)+(7*0)+(6*5)+(5*9)+(4*6)+(3*0)+(2*2)+(1*9)=120
120 % 10 = 0
So 105960-29-0 is a valid CAS Registry Number.

105960-29-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-Chloro-4-hydroxybenzyl alchol

1.2 Other means of identification

Product number -
Other names 2-Chlor-4-hydroxymethyl-phenol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:105960-29-0 SDS

105960-29-0Relevant articles and documents

PRODRUGS OF FUSED-BICYCLIC C5aR ANTAGONISTS

-

Paragraph 0248, (2019/10/23)

The present disclosure provides, inter alia, Compounds of Formulae IA, IB, IC, IIA, IIB and IIC or pharmaceutically acceptable salts thereof that are modulators of the C5a receptor. Also provided are pharmaceutical compositions and methods of use including the treatment of diseases or disorders involving pathologic activation from C5a and non-pharmaceutical applications.

Phenolic Oxidation Using H2O2 via in Situ Generated para-Quinone Methides for the Preparation of para-Spiroepoxydienones

McLaughlin, Michael F.,Massolo, Elisabetta,Cope, Thomas A.,Johnson, Jeffrey S.

supporting information, p. 6504 - 6507 (2019/09/04)

Phenols are attractive starting materials for the preparation of highly substituted cyclohexane rings via dearomative processes. Herein we report an efficient preparation of dearomatized 1-oxaspiro[2.5]octa-4,7-dien-6-ones (para-spiroepoxydienones) via the nucleophilic epoxidation of in situ generated para-quinone methides from 4-(hydroxymethyl)phenols using aqueous H2O2. The developed protocol bypasses the need for stoichiometric bismuth reagents or diazomethane, which are frequently deployed for p-spiroepoxydienone preparation. The p-spiroepoxydienones are further elaborated in numerous downstream complexity-building transformations.

AROMATASE INHIBITOR

-

Page/Page column 87, (2011/04/14)

There is provided a compound of formula (I) wherein Z is selected from N and CR22, wherein R22 is H or a bond with D, wherein D is selected from a bond, C=O, and linear or branched hydrocarbon groups having a carbon chain of from 1 t

Prodrugs of anthracyclines for use in antibody-directed enzyme prodrug therapy

Florent, Jean-Claude,Dong, Xia,Gaudel, Gilbert,Mitaku, Sofia,Monneret, Claude,Gesson, Jean-Pierre,Jacquesy, Jean-Claude,Mondon, Martine,Renoux, Brigitte,Andrianomenjanahary, Solo,Michel, Sylvie,Koch, Michel,Tillequin, Fran?ois,Gerken, Manfred,Czech, Joerg,Straub, Rainer,Bosslet, Klaus

, p. 3572 - 3581 (2007/10/03)

A series of new prodrugs of daunorubicin and doxorubicin which are candidates for antibody-directed enzyme prodrug therapy (ADEPT) is reported. These compounds (25a,b,c and 32a,b,c) have been designed to generate cytotoxic drugs after activation with β-gl

Acetals as New 2′-O-Protecting Functions for the Synthesis of Oligoribonucleotides: Synthesis of Uridine Building Blocks and Evaluation of Their Relative Acid Stability

Matysiak, Stefan,Fitznar, Hans-Peter,Schnell, Ralf,Pfleiderer, Wolfgang

, p. 1545 - 1566 (2007/10/03)

A broad variety of new acyclic vinyl ethers (see 6-41) have been synthesized via the vinyl-interchange reaction of ethyl vinyl ether at room temperature using mercury(II) trifluoroacetate as a highly efficient catalyst. The appropriate vinyl ethers were r

Biologically Active Metabolites of Fungi, I.-Isolation, Synthesis, and Biological Activity of Coniothyriomycin as well as Bioassay of Analogous Open-Chain Imides

Krohn, Karsten,Franke, Claudia,Jones, Peter G.,Aust, Hans-Juergen,Draeger, Sigfried,Schulz, Barbara

, p. 789 - 798 (2007/10/02)

The mixed open-chain imide N-(3-chloro-4-hydroxyphenylacetyl)fumarate (1), named coniothyriomycin, was isolated as a metabolite of the fungus Coniothyrium.The natural product 1 and the analoguos imides 13-15 and 22-24 have been synthesized by base-catalyzed condensation of the imidates 12a-f with acid chlorides 6a-c or the mixed anhydride 21.The compounds 1 and 13-15 were shown to posess remarkable fungicidal and herbicidal activities in short-termed tests. Key Words: Fungal metabolites / Imides, open-chain / Fungicidal activity / Coniothriomycin

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