10602-04-7

Basic information

• Product Name: 4-ETHYNYLBENZYL ALCOHOL 97
• Synonyms: 4-ETHYNYLBENZYL ALCOHOL 97;(4-ethynylphenyl)Methanol;1-Ethynyl-4-(hydroxymethyl)benzene;4-Hydroxymethylphenylacetylene;4-Ethynyl-benzeneMethanol;4-Ethynylbenzyl alcohol 97%;Benzenemethanol,4-ethynyl-
• CAS NO: 10602-04-7
• Molecular Formula: C₉H₈O
• Molecular Weight: 132.161
• Product Categories: Alkynes;Organic Building Blocks;Terminal;Building Blocks;Chemical Synthesis;Organic Building Blocks
• Mol File: 10602-04-7.mol

Chemical Properties

• Melting Point: 40-44 °C(lit.)
• Boiling Point: 239.6±23.0℃ (760 Torr)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.08±0.1 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.0216mmHg at 25°C
• Refractive Index: 1.572
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 14.13±0.10(Predicted)
• CAS DataBase Reference: 4-ETHYNYLBENZYL ALCOHOL 97(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ETHYNYLBENZYL ALCOHOL 97(10602-04-7)
• EPA Substance Registry System: 4-ETHYNYLBENZYL ALCOHOL 97(10602-04-7)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36-42/43
• Safety Statements: 26-36
• WGK Germany: 2
• Hazardous Substances Data: 10602-04-7(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
4-Ethynylbenzyl alcohol is used as a key intermediate in the synthesis of complex organic molecules, such as platinum-acetylide dendrimers, rotaxanes, and arylacetylenes. Its unique structure allows for the formation of diverse molecular architectures with potential applications in various fields.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Ethynylbenzyl alcohol is used as a precursor to synthesize arylalkyne-tagged sugars, which are essential for the photoinduced glycosylation of cysteine-containing peptides. This process plays a crucial role in the development of novel drug candidates and therapeutic agents.
Used in Material Science:
4-Ethynylbenzyl alcohol can also act as a precursor to synthesize fluorescent probes through a Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) click reaction. These fluorescent probes are valuable tools in material science, as they can be used to study various biological processes and interactions at the molecular level.
Overall, 4-Ethynylbenzyl alcohol 97 is a versatile and valuable compound with a wide range of applications in chemical synthesis, pharmaceuticals, and material science, making it an essential component in the development of new technologies and products.

InChI:InChI=1/C9H8O/c1-2-8-3-5-9(7-10)6-4-8/h1,3-6,10H,7H2

Upstream product

• 10602-03-6 ethyl 4-ethynylbenzoate 
• 63697-96-1 4-Ethynylbenzaldehyde 
• 275386-60-2 4-(hydroxymethyl)-1-(trimethylsilylethynyl)benzene 
• 175203-59-5 4-[4-(hydroxymethyl)phenyl]-2-methylbut-3-yn-2-ol 
• 38846-64-9 2-ethynylbenzaldehyde 
• 51934-41-9 4-iodobenzoic acid ethyl ester 
• 150969-54-3 ethyl 4-(trimethylsilylethynyl)benzoate 
• 873-75-6 4-bromobenzenemethanol 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 75867-41-3 4-trimethylsilanylethynyl-benzoic acid methyl ester 
• 1122-91-4 4-bromo-benzaldehyde 
• 117569-57-0 4-(3-hydroxy-3-methylbut-1-ynyl)benzaldehyde 
• 766-96-1 4-bromo-1-ethynylbenzene 
• 18282-51-4 4-iodo-benzyl alcohol 

Downstream Products

• 10601-98-6 1-(Chloromethyl)-4-ethynylbenzene 
• 113331-97-8 methyl 5-hydroxy-7-<4-(1-hydroxymethyl)phenyl>hept-6-ynoate 
• 63697-96-1 4-Ethynylbenzaldehyde 
• 782450-49-1 (4R)-[4-(4-aminooxymethyl-phenyl)-[1,2,3]triazol-1-yl]-tetrahydro-furan-(3S)-ol 
• 870719-33-8 4-ethynylbenzyl 3,5-bis[3',4'-di(octan-1-yloxy)benzyloxy]benzoate 
• 870719-39-4 4-ethynylbenzyl 3,5-bis[3',4'-di((S)-3,7-dimethyloctan-1-yloxy)benzyloxy]benzoate 
• 870719-35-0 4-ethynylbenzyl 3,5-bis[3',4'-di(decan-1-yloxy)benzyloxy]benzoate 
• 870719-59-8 4-ethynylbenzyl 3,5-bis[3',4'-di(tetradecan-1-yloxy)benzyloxy]benzoate 
• 765912-25-2 (4-thiazol-2-ylethynyl-phenyl)-methanol 
• 1013026-53-3 (4-dodeca-1,3-diynyl-phenyl)-methanol 
• 933986-59-5 4-(morpholinomethyl)phenylacetylene 

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A Helical Polyphenylacetylene Having Amino Alcohol Moieties Without Chiral Side Groups as a Chiral Ligand for the Asymmetric Addition of Diethylzinc to Benzaldehyde

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