106270-42-2

Basic information

• Product Name: benzyl-(4,6-dimethyl-pyrimidin-2-yl)-amine
• Synonyms: benzyl-(4,6-dimethyl-pyrimidin-2-yl)-amine
• CAS NO: 106270-42-2
• Molecular Formula: C₁₃H₁₅N₃
• Molecular Weight: 213
• Mol File: 106270-42-2.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: benzyl-(4,6-dimethyl-pyrimidin-2-yl)-amine(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl-(4,6-dimethyl-pyrimidin-2-yl)-amine(106270-42-2)
• EPA Substance Registry System: benzyl-(4,6-dimethyl-pyrimidin-2-yl)-amine(106270-42-2)

Safety Data

• Hazardous Substances Data: 106270-42-2(Hazardous Substances Data)

Upstream product

• 4472-44-0 2-chloro-4,6-dimethylpyrimidine 
• 100-46-9 benzylamine 
• 123-54-6 acetylacetone 
• 2211-57-6 N-benzylguanidine 
• 99418-09-4 (4,6-dimethyl-pyrimidin-2-yl)-nitro-amine 
• 767-15-7 2-Amino-4,6-dimethylpyrimidine 
• 100-52-7 benzaldehyde 
• 100-51-6 benzyl alcohol 

Relevant articles and documents

Microwave-assisted simple synthesis of 2-anilinopyrimidines by the reaction of 2-chloro-4,6-dimethylpyrimidine with aniline derivatives

A series of 2-anilinopyrimidines including novel derivatives has been obtained from 2-chloro-4,6-dimethylpyrimidine by aromatic nucleophilic substitution with differently substituted anilines under microwave conditions. The substituents had a significant impact on the course and efficiency of the reaction. The results reported herein demonstrate the efficacy of microwaves in the synthesis of the title heterocyclic compounds as compared to the results obtained with conventional heating. The 2-anilinopyrimidines described are of potential bioactivity.

Iron phthalocyanine as an efficient and versatile catalyst for N-alkylation of heterocyclic amines with alcohols: One-pot synthesis of 2-substituted benzimidazoles, benzothiazoles and benzoxazoles

An efficient and versatile iron phthalocyanine catalyzed method has been developed for N-alkylation of various amines with alcohols. Readily available alcohols were used as alkylating agents for direct N-alkylation of aminobenzothiazoles, aminopyridines and aminopyrimidines. N-Alkylation of ortho-substituted anilines (-NH2, -SH and -OH) led to the synthesis of 2-substituted benzimidazoles, benzothiazoles and benzoxazoles in one pot.

One-pot two-step solvent-free rapid and clean synthesis of 2-(substituted amino)pyrimidines by microwave irradiation

abs A series of diversely 2-(substituted amino)pyrimidines (along with ring substitution) has been synthesized under solvent- and catalyst-free microwave conditions from substituted guanidines and β-diketones. The substituted guanidines are synthesized from (S)-methylisothiourea sulfate and different amines (various alkyl, aryl, or heterocyclic and also chiral amines) under microwave irradiation. These two-step reactions are performed in one-pot without isolating any intermediate. This protocol has been successfully applied for the synthesis of bisaminopyrimidines and 2-substituted aminopyrimidines containing chiral moiety where chirality remains undisturbed.