106593-37-7

Basic information

• Product Name: N-ALLYL-2-CHLOROPROPANAMIDE
• Synonyms: N-ALLYL-2-CHLOROPROPANAMIDE;propanamide, 2-chloro-N-2-propenyl-;N-allyl-2-chloropropanamide(SALTDATA: FREE)
• CAS NO: 106593-37-7
• Molecular Formula: C₆H₁₀ClNO
• Molecular Weight: 147.61
• Mol File: 106593-37-7.mol

Chemical Properties

• Boiling Point: 262.045°C at 760 mmHg
• Flash Point: 112.281°C
• Appearance: /
• Density: 1.052g/cm³
• Vapor Pressure: 0.011mmHg at 25°C
• Refractive Index: 1.454
• PKA: 14.19±0.46(Predicted)
• CAS DataBase Reference: N-ALLYL-2-CHLOROPROPANAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-ALLYL-2-CHLOROPROPANAMIDE(106593-37-7)
• EPA Substance Registry System: N-ALLYL-2-CHLOROPROPANAMIDE(106593-37-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 106593-37-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
N-ALLYL-2-CHLOROPROPANAMIDE is used as a building block for the synthesis of various pharmaceuticals, contributing to the development of new drugs and medications.
Used in Agrochemical Industry:
N-ALLYL-2-CHLOROPROPANAMIDE is used as a building block for the synthesis of agrochemicals, aiding in the production of pesticides and other agricultural chemicals.
Used in Dye and Pigment Industry:
N-ALLYL-2-CHLOROPROPANAMIDE is used as an intermediate in the manufacture of dyes and pigments, playing a role in the creation of colorants for various applications.
Used in Organic Compounds Synthesis:
N-ALLYL-2-CHLOROPROPANAMIDE is used as an intermediate in the synthesis of other organic compounds, contributing to the development of a wide range of chemical products.

InChI:InChI=1/C6H10ClNO/c1-3-4-8-6(9)5(2)7/h3,5H,1,4H2,2H3,(H,8,9)

Upstream product

• 107-11-9 1-amino-2-propene 
• 535-13-7 2-chloro-propanoic acid, ethyl ester 
• 139126-57-1 (+/-)-N-(2,2,2-Trifluoroethyl)-2-chloropropionamide 
• 7623-09-8 2-chloropropionyl chloride 
• 107-06-2 1,2-dichloro-ethane 

Downstream Products

• 162375-40-8 N-2'-propenyl-2-(phenylthio)propanamide 
• 162375-32-8 N-2'-propenyl-Z-3-chloro-2-(phenylthio)propenamide 

Relevant articles and documents

Bending and stretching actuation of soft materials through surface-initiated polymerization

A redhead: Surface-grafted hydrophilic polymer brushes (see picture) with high molecular weight and graft density caused reversible bending and stretching of soft polymeric substrates on a macroscale. The shape change of the substrate was tuned to respond to different stimuli including humidity, temperature, and pH. Copyright

Investigation of the synthetic and mechanistic aspects of the highly stereoselective transformation of α-thioamides to α-thio-β- chloroacrylamides

Treatment of a series of α-thioamides with N-chlorosuccinimide results in efficient transformation to the analogous α-thio-β- chloroacrylamides. The mechanistic pathway has been established through isolation and characterisation of intermediate compounds. The scope of the transformation has been explored - aryl and alkylthio substituents, primary, secondary and tertiary amides can be employed. In most instances, the chloroacrylamides are formed exclusively as the Z-stereoisomer; however, with tertiary propanamides or with amides derived from butanoic or pentanoic acid a mixture of E- and Z-stereoisomers is formed. The Royal Society of Chemistry.

Enzymatic Aminolysis and Transamidation Reactions

Chiral amides can be obtained from (+/-)-2-chloropropionate esters and a wide range of amines when the reaction is catalyzed by Candida cylindracea lipase.The enantioselection of the enzyme in this aminolysis reaction depends on the substrate and nucleoph

A SIMPLE PROCEDURE FOR THE PREPARATION OF CHIRAL AMIDES

Yeast lipase (Candida cylindracea) catalysed the reaction between ethyl (+/-)-2-chloropropionate and different aliphatic and aromatic amines yielding optically active amides.