108274-04-0

Basic information

• Product Name: 3-ribofuranosyl-4,9-dihydro-4,6,7-trimethyl-9-oxoimidazo(1,2-a)purine
• Synonyms: 3-ribofuranosyl-4,9-dihydro-4,6,7-trimethyl-9-oxoimidazo(1,2-a)purine
• CAS NO: 108274-04-0
• Molecular Formula: C15H19 N5 O5
• Molecular Weight: 0
• Mol File: 108274-04-0.mol

Chemical Properties

• Boiling Point: 824.7°Cat760mmHg
• Flash Point: 452.6°C
• Appearance: /
• Density: 1.79g/cm³
• Vapor Pressure: 8.38E-29mmHg at 25°C
• Refractive Index: 1.805
• CAS DataBase Reference: 3-ribofuranosyl-4,9-dihydro-4,6,7-trimethyl-9-oxoimidazo(1,2-a)purine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ribofuranosyl-4,9-dihydro-4,6,7-trimethyl-9-oxoimidazo(1,2-a)purine(108274-04-0)
• EPA Substance Registry System: 3-ribofuranosyl-4,9-dihydro-4,6,7-trimethyl-9-oxoimidazo(1,2-a)purine(108274-04-0)

Safety Data

• Hazardous Substances Data: 108274-04-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H19N5O5/c1-6-7(2)20-13(24)9-12(18(3)15(20)17-6)19(5-16-9)14-11(23)10(22)8(4-21)25-14/h5,8,10-11,14,21-23H,4H2,1-3H3/t8-,10-,11-,14?/m1/s1

Upstream product

• 114262-22-5 3,4-Dihydro-4,6,7-trimethyl-3-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-imidazo<1,2-a>purin-9-one 
• 115436-28-7 4,9-Dihydro-4,6-dimethyl-9-oxo-3-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-3H-imidazo<1,2-a>purine-7-carboxaldehyde 
• 577773-09-2 3-((2R,3R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-6,7-dimethyl-3,5-dihydro-imidazo[1,2-a]purin-9-one 
• 118-00-3 guanosine 
• 68768-34-3 3,4-Dihydro-4,6-dimethyl-3-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-imidazo<1,2-a>purin-9-one 
• 115436-29-8 3,4-Dihydro-7-(hydroxymethyl)-4,6-dimethyl-3-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-imidazo<1,2-a>purin-9-one 
• 132366-93-9 4,9-Dihydro-4,7-dimethyl-9-oxo-3-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-3H-imidazo<1,2-a>purine-6-carboxaldehyde 
• 114262-21-4 Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-(6,7-dimethyl-9-oxo-5,9-dihydro-imidazo[1,2-a]purin-3-yl)-tetrahydro-furan-3-yl ester 
• 52662-10-9 3,4-Dihydro-4,6-dimethyl-3-β-D-ribofuranosyl-9H-imidazo<1,2-a>purin-9-one 

Downstream Products

• 96881-39-9 7-methylwye 

Relevant articles and documents

AN EFFICIENT SYNTHESIS OF Y-NUCLEOSIDE (WYOSINE) BY REGIOSPECIFIC METHYLATION OF N4-DESMETHYLWYOSINE USING ORGANOZINC REAGENT

The reaction of the organozinc reagent, produced by the reaction of CH2I2 + Zn(C2H5)2 + glyme in diethylether at 20 deg C, regioselectively methylates the N4-nitrogen of N4-desmethylwyosine-triacetate 3 to give pure wyosine-triacetate 1e in 76percent isolated yield; no trace of the isomeric N5 methylated product is found in the latter reaction.Synthesis of a new congener of Y-nucleoside 1f is also reported for the first time from compound 5 in a high overall yield using a similar procedure.