108446-76-0 Usage
Uses
Used in Pharmaceutical Industry:
3-(3-BIPHENYL-4-YL-1-PHENYL-1H-PYRAZOL-4-YL)-ACRYLIC ACID is used as a building block for the synthesis of new drugs due to its distinctive molecular structure, which can be leveraged to create novel therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical field, 3-(3-BIPHENYL-4-YL-1-PHENYL-1H-PYRAZOL-4-YL)-ACRYLIC ACID is used as a component in the development of new agrochemicals, potentially enhancing crop protection and yield through its incorporation into innovative products.
Used in Materials Science:
3-(3-BIPHENYL-4-YL-1-PHENYL-1H-PYRAZOL-4-YL)-ACRYLIC ACID is utilized as a ligand in catalytic reactions within the realm of materials science, contributing to the advancement of new materials with improved properties.
Further research and testing are essential to fully explore the potential applications and properties of 3-(3-BIPHENYL-4-YL-1-PHENYL-1H-PYRAZOL-4-YL)-ACRYLIC ACID, ensuring its safe and effective use in these industries.
Check Digit Verification of cas no
The CAS Registry Mumber 108446-76-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,4,4 and 6 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 108446-76:
(8*1)+(7*0)+(6*8)+(5*4)+(4*4)+(3*6)+(2*7)+(1*6)=130
130 % 10 = 0
So 108446-76-0 is a valid CAS Registry Number.
InChI:InChI=1/C24H18N2O2/c27-23(28)16-15-21-17-26(22-9-5-2-6-10-22)25-24(21)20-13-11-19(12-14-20)18-7-3-1-4-8-18/h1-17H,(H,27,28)/p-1/b16-15+
108446-76-0Relevant articles and documents
Microwave-Assisted Synthesis of 3-(4-Pyrazolyl)propenoic Acids
Chornous, Vitaliy O.,Bratenko, Mykhaylo K.,Vovk, Mykhaylo V.
, p. 79 - 83 (2007/10/03)
Under microwave activation, pyrazole-4-carboxaldehydes react with malonic acid in the presence of a small amount of pyridine to give 3-(4-pyrazolyl)propenoic acids in high yields.
Azoles. 17. Beta-(4-pyrazol)acrylic and propionic acids and their anti-inflammatory activity
Bernard,Hulley,Molenda,Stochla,Wrzeciono
, p. 560 - 562 (2007/10/02)
beta-(4-Pyrazole)acrylic acids 22-28 were prepared by the Knoevenagel reaction of malonic acid and 4-formylpyrazoles 8-14. 4-Pyrazolemethylenemalonic acids 15-21 were isolated as intermediates. The latter compounds were also synthesized by treating the 4-formylpyrazoles 8-14 with diethyl malonate followed by hydrolysis of the obtained diethyl esters 15a-21a. The effect of piperidine and pyridine on the Knoevenagel condensation was investigated. The beta-(4-pyrazole)acrylic acids 22-27, on catalytic reduction, gave the corresponding beta-(4-pyrazole)propionic acids 29-34. Compounds 23, 24, 27, 29-31 and 34 appeared to be less active than phenylbutazone in carrageenin-induced oedema test, but they were less toxic than the reference drug.
