108446-64-6

Basic information

• Product Name: 3-BIPHENYL-4-YL-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE
• Synonyms: 3-Biphenyl-4-yl-1-phenyl-1H-pyrazole-4-carbaldehyde
• CAS NO: 108446-64-6
• Molecular Formula: C₂₂H₁₆N₂O
• Molecular Weight: 324.39
• Mol File: 108446-64-6.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 554.5 °C at 760 mmHg
• Flash Point: 289.1 °C
• Appearance: /
• Density: 1.13 g/cm³
• Vapor Pressure: 2.46E-12mmHg at 25°C
• Refractive Index: 1.63
• CAS DataBase Reference: 3-BIPHENYL-4-YL-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BIPHENYL-4-YL-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE(108446-64-6)
• EPA Substance Registry System: 3-BIPHENYL-4-YL-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE(108446-64-6)

Safety Data

• Hazardous Substances Data: 108446-64-6(Hazardous Substances Data)

Usage

General Description

3-BIPHENYL-4-YL-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE is a chemical compound with a complex molecular structure. It consists of three aromatic rings, including two biphenyl groups and a phenyl group, as well as a pyrazole ring and a carbonyl group. 3-BIPHENYL-4-YL-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE is important in organic chemistry and pharmaceutical research due to its potential applications in drug development and material science. It may have biological activities or be used as a building block in the synthesis of other chemical compounds. The precise properties and potential uses of this chemical may vary depending on the specific context and conditions in which it is being studied or applied.

InChI:InChI=1/C22H16N2O/c25-16-20-15-24(21-9-5-2-6-10-21)23-22(20)19-13-11-18(12-14-19)17-7-3-1-4-8-17/h1-16H

Upstream product

• 3724-43-4 Vilsmeier reagent 
• 108446-63-5 1-(1-biphenyl-4-yl-ethylidene)-2-phenylhydrazine 
• 92-91-1 biphenyl-4-acetaldehyde 
• 68-12-2 N,N-dimethyl-formamide 
• 100-63-0 phenylhydrazine 
• 1373224-00-0 C₄₀H₃₄N₄S 
• 108446-63-5 1-biphenyl-4-yl-ethanone-phenylhydrazone 

Downstream Products

• 108446-76-0 (E)-3-(3-Biphenyl-4-yl-1-phenyl-1H-pyrazol-4-yl)-acrylic acid 
• 108446-71-5 2-(3-Biphenyl-4-yl-1-phenyl-1H-pyrazol-4-ylmethylene)-malonic acid 
• 475626-39-2 2-{[3-(biphenyl-4-yl)-1-phenyl-1H-pyrazol-4-yl]methylene}-hydrazinecarbothioamide 
• 1357384-09-8 2-{[[3-(biphenyl-3-yl)-1-phenyl-1H-pyrazol-4-yl]methylene]-hydrazono}-3-(β-D-glucopyranosyl)-4-phenyl-2,3-dihydrothiazole 
• 1357384-10-1 2-{2-[[[3-(biphenyl-3-yl)-1-phenyl-1H-pyrazol-4-yl]methylene]hydrazono]-4-phenylthiazol-3(2H)-yl}-N'-(4-chlorobenzylidene)acetohydrazide 
• 1357384-11-2 2-{2-[[[3-(biphenyl-3-yl)-1-phenyl-1H-pyrazol-4-yl]methylene]-hydrazono]-4-phenylthiazol-3(2H)-yl}-N'-(3,4,5-trimethoxybenzylidene)acetohydrazide 
• 1357384-12-3 D-galactose 2-{2-[[(3-(biphenyl-3-yl)-1-phenyl-1H-pyrazol-4-yl)methylene]hydrazono]-4-phenylthiazol-3(2H)-yl}acetohydrazone 
• 1357384-13-4 D-mannose 2-{2-[[(3-(biphenyl-3-yl)-1-phenyl-1H-pyrazol-4-yl)methylene]hydrazono]-4-phenylthiazol-3(2H)-yl}acetohydrazone 
• 1357384-14-5 D-xylose 2-{2-[[(3-(biphenyl-3-yl)-1-phenyl-1H-pyrazol-4-yl)methylene]hydrazono]-4-phenylthiazol-3(2H)-yl}acetohydrazone 
• 1357384-15-6 2,3,4,5,6-penta-O-acetyl-D-galactose-2-{2-[[(3-(biphenyl-3-yl)-1-phenyl-1H-pyrazol-4-yl)methylene]-hydrazono]-4-phenylthiazol-3(2H)-yl}acetohydrazone 
• 1357384-16-7 2,3,4,5,6-penta-O-acetyl-D-mannose-2-{2-[[(3-(biphenyl-3-yl)-1-phenyl-1H-pyrazol-4-yl)methylene]-hydrazono]-4-phenylthiazol-3(2H)-yl}acetohydrazone 
• 1357384-17-8 2,3,4,5-tetra-O-acetyl-D-xylose-2-{2-[[(3-(biphenyl-3-yl)-1-phenyl-1H-pyrazol-4-yl)methylene]-hydrazono]-4-phenylthiazol-3(2H)-yl}acetohydrazone 
• 1357384-03-2 2-{[[3-(biphenyl-4-yl)-1-phenyl-1H-pyrazol-4-yl]methylene]-hydrazono}-4-phenyl-2,3-dihydrothiazole 
• 1357384-04-3 ethyl 2-{2-[[(3-(biphenyl-3-yl)-1-phenyl-1H-pyrazol-4-yl)methylene]hydrazono]-4-phenylthiazol-3(2H)-yl}acetate 

Relevant articles and documents

Temperature-dependent product selectivity in the Vilsmeier-Haack reaction on bis(phenylhydrazones) of bis(aroylmethyl) sulfides (=1,1'-[thiobis(methylene) ]bis[arylmethanone] bis(2-phenylhydrazones)): Synthesis of 3-aroylindoles (=aryl(1H-indol-3-yl)methanones)

The bis(phenylhydrazone) of substituted diphenacyl sulfides (=1,1'-[thiobis(methylene)]bis[arylmethanone] bis(2-phenylhydrazones)) 1 underwent a tandem sequence of reactions upon treatment with Vilsmeier reagent, ultimately yielding 3-aroylindoles (=aryl(1H-indol-3-yl)methanones) 3 (Scheme 1 and Table 1). The reaction seems to be product selective depending upon the reaction temperature. Copyright

Phenyl pyrazole compound, pharmaceutical composition and preparation method and application of phenyl pyrazole compound

The invention discloses a phenyl pyrazole compound, a pharmaceutical composition and a preparation method and application of the phenyl pyrazole compound. The phenyl pyrazole compound shown in a formula I or a formula II can be used for preparing drugs fo

Synthesis, antiviral, cytotoxicity and antitumor evaluations of A4 type of porphyrin derivatives

This manuscript describes the synthesis of a new series of porphyrin structures 4a-4m, 7, 9, 12 and 14. These structures were investigated against two types of viruses such as HIV-1 and HSV-1. Also they were screened for their antitumor activity. Among all tested compounds, it was found that compound 4b showed a high activity against HIV-1 and HSV-1 and against four different tumor cell lines. Most of the tested compounds showed a moderate degree of a potent antimicrobial activity. The structure of these compounds was confirmed on the basis of their analytical and spectral data such as UV-vis, IR, 13C NMR, 1H NMR spectroscopy and mass spectral data.