108540-96-1Relevant articles and documents
N-Aryl Amides as Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Contrast Agents
Cai, Xuekang,Zhang, Jia,Lu, Jiaqi,Yi, Long,Han, Zheng,Zhang, Shuixing,Yang, Xing,Liu, Guanshu
supporting information, p. 11705 - 11709 (2020/08/13)
Chemical exchange saturation transfer (CEST) MRI has recently emerged as a versatile molecular imaging approach in which diamagnetic compounds can be utilized to generate an MRI signal. To expand the scope of CEST MRI applications, herein, we systematical
Coolade. A Low-Foaming Surfactant for Organic Synthesis in Water
Lee, Nicholas R.,Cortes-Clerget, Margery,Wood, Alex B.,Lippincott, Daniel J.,Pang, Haobo,Moghadam, Farbod A.,Gallou, Fabrice,Lipshutz, Bruce H.
, p. 3159 - 3165 (2019/04/26)
Several types of reduction reactions in organic synthesis are performed under aqueous micellar-catalysis conditions (in water at ambient temperature), which produce a significant volume of foam owing to the combination of the surfactant and the presence of gas evolution. The newly engineered surfactant “Coolade” minimizes this important technical issue owing to its low-foaming properties. Coolade is the latest in a series of designer surfactants specifically tailored to enable organic synthesis in water. This study reports the synthesis of this new surfactant along with its applications to gas-involving reactions.
Radical-mediated dehydrative preparation of cyclic imides using (NH4)2S2O8-DMSO: Application to the synthesis of vernakalant
Garad, Dnyaneshwar N.,Tanpure, Subhash D.,Mhaske, Santosh B.
supporting information, p. 1008 - 1016 (2015/08/18)
Ammonium persulfate-dimethyl sulfoxide (APS-DMSO) has been developed as an efficient and new dehydrating reagent for a convenient one-pot process for the synthesis of miscellaneous cyclic imides in high yields starting from readily available primary amines and cyclic anhydrides. A plausible radical mechanism involving DMSO has been proposed. The application of this facile one-pot imide forming process has been demonstrated for a practical synthesis of vernakalant.
Reactions of Cyclic Anhydrides: Part XIII - Facile Synthesis of 1,2,3,4-Tetrahydro-10H-pyridazinoquinazoline-2,10-diones
Balasubramaniyan, V.,Argade, N. P.
, p. 906 - 908 (2007/10/02)
1,2,3,4-Tetrahydro-10H-pyridazinoquinazoline-2,10-diones have been prepared by hydrazinolysis of o-alkoxycarbonylsuccinanilic acids (IIIa-d), alkyl o-alkoxycarbonylsuccinanilates (IVa-f) or alkyl β-(4-oxo-3,1-benzoxazin-2-yl)propionates (Va,b) via