109028-09-3

Basic information

• Product Name: 7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo-[1,2-a]quinoxaline maleate salt
• Synonyms: 7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo-[1,2-a]quinoxaline maleate salt;CGS-12066A maleate salt;7-(Trifluoromethyl)-4-(4-methylpiperazin-1-yl)pyrrolo[1,2-a]quinoxaline;7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo[1,2-a]quinoxaline;CGS-12066;Pyrrolo[1,2-a]quinoxaline,4-(4-methyl-1-piperazinyl)-7-(trifluoromethyl)-
• CAS NO: 109028-09-3
• Molecular Formula: C17H17F3N4C4H4O4
• Molecular Weight: 334.34
• Mol File: 109028-09-3.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: 7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo-[1,2-a]quinoxaline maleate salt(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo-[1,2-a]quinoxaline maleate salt(109028-09-3)
• EPA Substance Registry System: 7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo-[1,2-a]quinoxaline maleate salt(109028-09-3)

Safety Data

• Hazardous Substances Data: 109028-09-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo-[1,2-a]quinoxaline maleate salt is used as a pharmacological agent for its 5-HT1 activity in mammals. This activity is related to the regulation of mood through its interaction with serotonin, a neurotransmitter that plays a crucial role in mood regulation, appetite, and sleep. The compound's ability to modulate serotonin levels makes it a potential candidate for the development of treatments for various mood disorders and conditions related to serotonin dysregulation.

Upstream product

• 109-01-3 1-methyl-piperazine 
• 136773-68-7 4-Chloro-7-trifluoromethyl-pyrrolo[1,2-a]quinoxaline 
• 136773-66-5 7-(trifluoromethyl)pyrrolo<1,2-a>quinoxalin-4(5H)-one 
• 136773-58-5 1H–1–(4–trifluoromethyl–2–nitrophenyl)pyrrole 
• 136773-59-6 1-<2-nitro-4-(trifluoromethyl)phenyl>-1H-pyrrole-2-carbonitrile 
• 136773-65-4 1-<2-nitro-4-(trifluoromethyl)phenyl>-1H-pyrrole-2-carboxamide 
• 400-98-6 4-trifluoromethyl-2-nitroaniline 

Relevant articles and documents

Novel and highly potent 5-HT3 receptor agonists based on a pyrroloquinoxaline structure

The synthesis and the biological evaluation of a series of novel pyrroloquinoxaline derivatives are described. In binding studies several compounds proved to be potent and selective 5-HT3 receptor ligands. The most active pyrroloquinoxalines, 1

Polycondensed heterocycles. VII. A convenient synthesis of pyrrolo[1,2-a]quinoxaline derivatives by intramolecular aromatic nucleophilic displacement

4-(4-Methyl-1-piperazinyl)-7- trifluoromethylpyrrolo[1,2-a]quinoxaline (CGS 12066B) and related analogs were prepared in good overall yield through a reaction sequence involving as a key step in the intramolecular substitution of aromatic fluoride or nitr