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Methanone, (4-chloro-3-pyridinyl)phenyl- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 109575-05-5 Structure
  • Basic information

    1. Product Name: Methanone, (4-chloro-3-pyridinyl)phenyl-
    2. Synonyms:
    3. CAS NO:109575-05-5
    4. Molecular Formula: C12H8ClNO
    5. Molecular Weight: 217.655
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 109575-05-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Methanone, (4-chloro-3-pyridinyl)phenyl-(CAS DataBase Reference)
    10. NIST Chemistry Reference: Methanone, (4-chloro-3-pyridinyl)phenyl-(109575-05-5)
    11. EPA Substance Registry System: Methanone, (4-chloro-3-pyridinyl)phenyl-(109575-05-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 109575-05-5(Hazardous Substances Data)

109575-05-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 109575-05-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,9,5,7 and 5 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 109575-05:
(8*1)+(7*0)+(6*9)+(5*5)+(4*7)+(3*5)+(2*0)+(1*5)=135
135 % 10 = 5
So 109575-05-5 is a valid CAS Registry Number.

109575-05-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name (4-chloropyridin-3-yl)-phenylmethanone

1.2 Other means of identification

Product number -
Other names 3-Benzoyl-4-chloropyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:109575-05-5 SDS

109575-05-5Relevant articles and documents

COMPOUNDS AND METHODS FOR HEMATOPOIETIC REGENERATION

-

Page/Page column 66; 71-72, (2019/06/17)

The invention relates to compounds that promote hematopoietic regeneration. The invention further relates to methods of promoting hematopoietic regeneration using the novel compounds of the invention.

Palladium catalyzed addition of arylboronic acid or indole to nitriles: Synthesis of aryl ketones

Das, Tuluma,Chakraborty, Amarnath,Sarkar, Amitabha

supporting information, p. 7198 - 7202 (2015/01/09)

Aryl ketones can be synthesized conveniently by a palladium catalyzed addition of arylboronic acid to nitriles in aqueous triflic acid. This catalytic system was extended to the addition of unprotected indoles to nitriles under a slightly modified condition to produce 3-acyl indoles in good yields.

Discovery of 2-(1H-indazol-1-yl)-thiazole derivatives as selective EP 1 receptor antagonists for treatment of overactive bladder by core structure replacement

Atobe, Masakazu,Naganuma, Kenji,Kawanishi, Masashi,Morimoto, Akifumi,Kasahara, Ken-Ichi,Ohashi, Shigeki,Suzuki, Hiroko,Hayashi, Takahiko,Miyoshi, Shiro

, p. 1327 - 1333 (2014/03/21)

We have designed a series of potent EP1 receptor antagonists. These antagonists are a series of 2-(1H-indazol-1-yl)-thiazoles in which the core structure was replaced with pyrazole-phenyl groups. In preliminary conscious rat cystometry experiments, two representative candidates, 2 and 22, increased bladder capacity. In particular, the increase using 22 was approximately 2-fold that of the baseline. More detailed profiling of this compound and further optimization of this series promises to provide a novel class of drug for treating overactive bladder (OAB).

Vilsmeier reaction of 3-aminopropenamides: One-pot synthesis of pyrimidin-4(3 H)-ones

Zhang, Rui,Zhang, Dingyuan,Liang, Yongjiu,Zhou, Guangyuan,Dong, Dewen

experimental part, p. 2880 - 2883 (2011/05/28)

A facile one-pot synthesis of pyrimidin-4(3H)-ones was developed via reactions of a series of readily available 3-aminopropenamides with varied Vilsmeier reagents, and a mechanism involving sequential halogenation, formylation, and intramolecular nucleoph

BICYCLIC NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS

-

Page/Page column 68-69, (2010/03/02)

A nitrogen-containing bicyclic heterocyclic compound represented by the following formula (1) is provided. When the compound or a salt thereof is administered to a human being or an animal, the compound has a strong antagonistic action against EP1 recepto

Enantioselective synthesis of 4-(dimethylamino)pyridines through a chemical oxidation-enzymatic reduction sequence. Application in asymmetric catalysis

Busto, Eduardo,Gotor-Fernandez, Vicente,Gotor, Vicente

, p. 2626 - 2632 (2007/10/03)

Enantiomerically pure 4-(dimethylamino)-3-(1-hydroxyalkyl)pyridines and 4-(dimethylamino)-3-[hydroxy(phenyl)methyl]pyridine have been prepared through efficient chemoenzymatic routes. For this purpose different lipases and oxidoreductases have been tested

Directed Lithiation of 4-Halopyridines: Chemoselectivity, Regioselectivity and Application to Synthesis

Marsais, F.,Trecourt, F.,Breant, P.,Queguiner, G.

, p. 81 - 87 (2007/10/02)

4-Chloro and 4-fluoropyridines were ortho-lithiated by n-butyllithium-TMEDA chelate or lithium diisopropylamide at low temperature.The resulting 3-lithio 4-halopyridines were reacted with electrophiles which led to various 3,4-disubstituted pyridines.The versatility of this functionalization is enhanced by the 4-halogen reactivity towards nucleophiles such as water, methylate and amines.Some of the 3,4-disubstituted synthons were annelated to naphthyridine, xanthone and coumarin or condensed to Hantzsch-ester or to "chlotrimazol" analogues.Lithiation of 4-fluoropyridine led in one step to 3,4-pyridyne, which was trapped by cycloaddition with furans.

Synthesis of 4-Amino-3-pyridinyl and 4-Amino-5-pyrimidinyl Aryl Ketones and Related Compounds via an ortho-Lithiation Reaction

Radinov, Rumen,Haimova, Marietta,Simova, Ekaterina

, p. 886 - 891 (2007/10/02)

4-Chloropyridine and 4,6-dichloropyrimidine react regioselectively with lithium diisopropylamide to give 4-chloro-3-lithiopyridine and 4,6-dichloro-5-lithiopyrimidine, respectively.These intermediates react with benzaldehydes to give (4-chloro-3-pyridinyl

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