The invention provides compounds for use in treating microbial infection in an animal. Example compounds include Pyridin-3-ylmethyl (4-((2-aminophenyl)- carbamoyl)benzyl)carbamate ("Entinostat"). The compounds can act via induction of the innate antimicrobial peptide defense system, and stimulation of autophagy.
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Page/Page column 37
(2015/05/19)
Synthesis of 2,5(6)-Disubstituted-benzimidazoles, 2-Substituted-5-(4-substituted-phenyl)-1,3,4-thiadiazoles and Imidazothioxanthene and Their Antifilarial Activity
2-Carbomethoxyaminothioxanthenoimidazol-12-one-13,13-dioxide (5), 2,5(6)-disubstituted-benzimidazoles (10-13) and 2-substituted-5-(3-nitro-4-substituted-phenyl)-1,3,4-thiadiazoles (18-24) have been synthesized and evaluated for their antifilarial a
Chauhan, P. M. S.,Bhakuni, D. S.
p. 1146 - 1149
(2007/10/02)
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