- Alkyne Insertion into Ruthenium-Carbon Bonds: Formation and Ring-closing Reactions of Vinyl Complexes
-
Compounds react with to yield vinyl complexes (2a)-(2d).The mechanism of formation appears to involve CO substitution by the alkyne, combination of alkyne a
- Crook, Joseph R.,Chamberlain, Barbara,Mawby, Roger J.
-
-
Read Online
- Decarboxylative olefination of potassium benzoates via bimetallic catalysis strategy
-
Abstract: A novel synthesis of styrene derivatives through decaroxylative olefination of potassium benzoates with alkynes using Pd2dba3/CuBr as catalyst system has been developed. The protocol proceeded smoothly and in most cases Z-alkene was the main product. Electron-rich potassium benzoates reacted more efficiently than those of electron-deficient substrates. Heteroaromatic and electron-deficient aryl alkynes were not consistent with this transformation. Graphical abstract: [Figure not available: see fulltext.].
- Khalaj, Mehdi,Ghazanfarpour-Darjani, Majid,Taheri, Saeed,Sedaghat, Sajjad,Hoseyni, Seyed Jalal
-
p. 2013 - 2019
(2018/09/25)
-
- Asymmetric hydrogenation of maleic acid diesters and anhydrides
-
Asymmetric hydrogenation of maleic and fumaric acid derivatives with iridium catalysts based on N,P ligands provides an efficient route to chiral enantioenriched succinates. A new catalyst derived from a 2,6-difluorophenyl- substituted pyridine-phosphinite ligand was developed and enables the conversion of a wide range of 2-alkyl and 2-arylmaleic acid diesters into the corresponding succinates in high enantiomeric purity. Mixtures of cis/trans substrates can be hydrogenated in an enantioconvergent fashion with high enantioselectivity, and further enhances the scope of this transformation. The products are valuable chiral building blocks with a structural motif found in many bioactive compounds, such as metalloproteinase inhibitors. An attractive enantioselective route to 2-alkyl- and 2-aryl-substituted succinic acid derivatives is opened up by the asymmetric hydrogenation of maleic and fumaric acid derivatives, using the new catalyst [Ir(cod)L]BArF, derived from a 2,6-difluorophenyl-substituted pyridine-phosphinite ligand. The products are valuable chiral building blocks having a structural motif found in many bioactive compounds. cod=1,5-cyclooctadiene.
- Bernasconi, Maurizio,Mueller, Marc-Andre,Pfaltz, Andreas
-
supporting information
p. 5385 - 5388
(2014/06/09)
-