110167-20-9

Basic information

• Product Name: 4-BENZYL-3-HYDROXYMETHYLMORPHOLINE
• Synonyms: 4-BENZYL-3-HYDROXYMETHYLMORPHOLINE;N-Benzyl-3-(hydroxymethyl)morpholine;4-Benzyl-3-MorpholineMethanol;(4-Benzylmorpholin-3-yl)
• CAS NO: 110167-20-9
• Molecular Formula: C₁₂H₁₇NO₂
• Molecular Weight: 207.26888
• Product Categories: pharmacetical
• Mol File: 110167-20-9.mol

Chemical Properties

• Boiling Point: 322.7±22.0 °C(Predicted)
• Appearance: /
• Density: 1.117±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 14.85±0.10(Predicted)
• CAS DataBase Reference: 4-BENZYL-3-HYDROXYMETHYLMORPHOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BENZYL-3-HYDROXYMETHYLMORPHOLINE(110167-20-9)
• EPA Substance Registry System: 4-BENZYL-3-HYDROXYMETHYLMORPHOLINE(110167-20-9)

Safety Data

• Hazardous Substances Data: 110167-20-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-BENZYL-3-HYDROXYMETHYLMORPHOLINE is used as an intermediate in the synthesis of pharmaceuticals for its potential applications in the development of anti-cancer drugs and anti-inflammatory agents. Its unique structure allows for the creation of novel therapeutic agents that can target specific biological pathways.
Used in Agrochemical Industry:
In the agrochemical sector, 4-BENZYL-3-HYDROXYMETHYLMORPHOLINE is utilized as a precursor in the production of various agrochemicals, contributing to the development of effective pest control and crop protection solutions.
Used in Organic Synthesis:
4-BENZYL-3-HYDROXYMETHYLMORPHOLINE is used as a building block in organic synthesis due to its benzyl group, which provides a platform for further chemical reactions and the creation of new organic compounds with diverse applications in various industries.
Overall, 4-BENZYL-3-HYDROXYMETHYLMORPHOLINE's multifaceted applications in the pharmaceutical, agrochemical, and chemical industries underscore its significance as a key compound in modern chemical research and development.

Upstream product

• 106910-76-3 (RS)-N-benzylserine 
• 106910-79-6 (RS)-4-benzyl-5-oxomorpholine-3-carboxylic acid 
• 106910-78-5 (RS)-N-benzyl-N-chloroacetylserine 
• 100-52-7 benzaldehyde 

Downstream Products

• 110167-23-2 phenyl 3-(4-chlorophenoxy)methylmorpholine-4-carboxylate 
• 110167-24-3 phenyl 6-(4-chlorophenoxy)-1,4-oxazepane-4-carboxylate 
• 106910-83-2 (rac)-3-hydroxymethylmorpholine 
• 114368-08-0 4-benzyl-3-chloromethylmorpholine hydrochloride 
• 885954-25-6 4-benzyl-morpholine-3-carbaldehyde 
• 1033235-08-3 N-benzyl-3-vinylmorpholine 
• 913718-59-9 4-benzyl-3-(iodomethyl)mopholine 
• 833474-06-9 tert-butyl 3-formylmorpholine-4-carboxylate 
• 473923-56-7 tert-Butyl 3-(hydroxymethyl)-4-morpholinecarboxylate 
• 110167-16-3 N-benzyl-3-(chloromethyl)morpholine 
• 110167-28-7 6-(4-chlorophenoxy)-1,4-oxazepane oxalate 
• 111950-08-4 4-benzylmorpholin-3-ylacetic acid hydrochloride 
• 110167-26-5 3-(4-chlorophenoxy)methylmorpholine hydrochloride 
• 111949-90-7 (4-benzylmorpholin-3-yl)acetonitrile 

Relevant articles and documents

FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS

A series of 5,6-dihydro-l,3-benzothiazol-7(4H)-one derivatives, and analogues thereof, which are substituted in the 2-position by an optionally substituted morpholin-4-yl moiety, being selective inhibitors of PD kinase enzymes, are accordingly of b.enefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.

3-arylcarbonyl-1-(C-attached-N-heteryl)-1H-indoles

2-R2 -R4 -substituted-3-R3 -CO-1-[(C-attached-N-herteryl)-(Alk)n ]-1H-indoles useful as analgesic, anti-rheumatic, anti-inflammatory or anti-glaucoma agents.

Chiral Synthesis of 3-Substituted Morpholines via Serine Enantiomers and Reductions of 5-Oxomorpholine-3-carboxylates

The chiral synthesis of 3-hydroxymethyl- and 3-carboxy-morpholines from serine enantiomers is described.Chemoselective and total reductions of 5-oxomorpholine-3-carboxylates are key synthetic steps.