There are disclosed compounds of the formula STR1 wherein X is N or CR2 Y is O, S, NR2, CHR2 or C(R2)2 when n=0, or N or CR2 when n=1; p is 0-3; R1 is STR2 R2 is hydro
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(2008/06/13)
Phenylephrine Derivatives as Leukotriene D4 Antagonists
Two series of phenylephrine derivatives were prepared and tested as inhibitors of leukotriene D4 (LTD4) induced and ovalbumin-induced bronchospasm in the guinea pig.The most potent compound of the urea series, (R)-N,N-diethyl-N-2-hy
Musser, John H.,Kubrak, Dennis M.,Bender, Reinhold H. W.,Kreft, Anthony F.,Nielsen, Susan T.,et al.
p. 2087 - 2093
(2007/10/02)
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