19547-38-7Relevant articles and documents
Synthesis, DNA-binding and photocleavage of "light switch" complexes [Ru(bpy)2(pyip)]2+ and [Ru(phen) 2(pyip)]2+
Liu, Xue-Wen,Shen, You-Ming,Lu, Ji-Lin,Chen, Yuan-Dao,Li, Lin,Zhang, Da-Shun
, p. 522 - 527 (2010)
Two novel Ru(II) complexes [Ru(bpy)2(pyip)]2+ 1 and [Ru(phen)2(pyip)]2+ 2 (bpy = 2,2′-bipyridine; phen = 1,10-phenanthroline; pyip = 2-(pyridine-2-yl)imidazo-[4,5-f][1,10]- phenanthroline), have been synthesized and characterized by elemental analysis, ES-MS, 1H NMR, UV-Vis. The DNA-binding behaviors of both complexes were studied by spectroscopic methods and viscosity measurements. The results indicate that the two complexes can bind to CT-DNA in an intercalative mode, and also show that these two Ru(II) complexes can promote the photocleavage of pBR322 DNA. In addition, In the presence of Co2+, the emission of DNA-[Ru(L)2pyip]2+ can be quenched, which exhibited the DNA "light switch" properties.
Tetranuclear Lanthanide Complexes Containing a Hydrazone-type Ligand. Dysprosium [2 × 2] Gridlike Single-Molecule Magnet and Toroic
Gusev, Alexey,Herchel, Radovan,Nemec, Ivan,Shul'gin, Victor,Eremenko, Igor L.,Lyssenko, Kostantin,Linert, Wolfgang,Trávní?ek, Zdeněk
, p. 12470 - 12476 (2016)
A multidentate hydrazone-type ligand (Z,Z)-bis(1-(pyridin-2-yl)-1-amino-methylidene)oxalohydrazide (H2L) was utilized in the synthesis of three new isomorphous tetranuclear complexes of the general formula [Ln4(HL)4(H2L)2(NO3)4](NO3)4·4CH3OH (Ln = GdIII, 1, TbIII, 2, DyIII, 3) with the gridlike [2 × 2] topology. The analysis of the static magnetic data revealed weak anti-ferromagnetic interaction among lanthanide(III) atoms, whereas dynamic magnetic data led to the observation of the single-molecule magnet behavior in zero static magnetic field for the Dy4 compound 3 with Ueff = 42.6 K and τ0 = 1.50 × 10-5 s. The theoretical CASSCF calculations supported also the presence of the net toroidal magnetic moment, which classifies compound 3 also as a single-molecule toroic.
In vitro and in vivo biological effects of novel arylimidamide derivatives against Trypanosoma cruzi
Timm, Bruno Lisboa,Da Silva, Patricía Bernadino,Batista, Marcos Meuser,Da Silva, Francisca Hildemagna Guedes,Da Silva, Cristiane Fran?a,Tidwell, Richard R.,Patrick, Donald A.,Jones, Susan Kilgore,Bakunov, Stanislav A.,Bakunova, Svetlana M.,Soeiro, Maria De Nazaré C.
, p. 3720 - 3726 (2014)
Chagas disease (CD), a neglected tropical disease caused by Trypanosoma cruzi, remains a serious public health problem in several Latin American countries. The available chemotherapies for CD have limited efficacy and exhibit undesirable side effects. Aro
Self assembled tetranuclear Cu4(ii), Ni4(ii) [2 × 2] square grids and a dicopper(ii) complex of heterocycle based polytopic ligands - Magnetic studies
Mandal, Tarak Nath,Roy, Somnath,Konar, Saugata,Jana, Atanu,Ray, Sangita,Das, Kinsuk,Saha, Rajat,El Fallah, Mohamed Salah,Butcher, Ray J.,Chatterjee, Sudipta,Kar, Susanta Kumar
, p. 11866 - 11875 (2011)
The ditopic ligand PyPzOAP (N-[(Z)-amino(pyridin-2-yl)methylidene]-5- methyl-1-(pyridin-2-yl)-1H-pyrazole-3-carbohydrazonic acid) and the polytopic ligand 2-PzCAP (N′3,N′5-bis[(1E)-1-(pyridin-2- yl)ethylidene]-1H-pyrazole-3,5-dicarbo
Cyanoamidines. I. Synthesis and vasodilatory activity of N-substituted heteroaromatic cyanoamidines
Nakajima,Izawa,Kashiwabara,Nakajima,Munezuka
, p. 2475 - 2482 (1994)
Various heteroaromatic cyanoamidines were synthesized starting from nitriles via cyanoimidates or from amides via thioamides. The compounds were tested for inhibitory effect on the 40 mM K+-induced contraction of rat aorta strips and selected compounds were also evaluated for antagonism of the norepinephrine-induced contraction. Most of the cyanoamidines showed vasodilatory activities. Potent vasoactive compounds were also examined for stimulation of the 86Rb+ efflux to determine their potassium channel opening actions. Maximum potency was displayed by N-cyano-N'-(2-nitroxyethyl)-3-pyridinecarboxamidine (3h). The methanesulfonate of 3h, which was designated as KRN2391, has been selected for further development as an antianginal agent.
The First Dinuclear μ-Hexafluorosilicato Copper(II) Compound. Synthesis and Crystal Structure of (μ-Hexafluorosilicato-κF:κF')-bis3-salicyloylpyridine-2-carboxamidrazonato-κ3N',N2,O)copper(II)> Dihydrate
Koningsbruggen, Petra J. van,Haasnoot, Jaap G.,Graaff, Rudolf A. G. de,Reedijk, Jan
, p. 483 - 484 (1993)
The X-ray structure of a unique dinuclear copper(II) compound containing a single hexafluorosilicato bridge, *2H2O (HL = N3-salicyloylpyridine-2-carboxamidrazone), is reported.
Synthesis of 2-pyridyl oxazoline esters and their organocatalytic application to the enantioselective silane reduction of ketones
Cao, Zhenyu,McCleary, Nadine,O’Leary, Patrick
, p. 350 - 367 (2019)
The synthesis of a number of novel chiral 2-pyridyl oxazoline esters is reported along with the use of these in the enantioselective organocatalytic reduction of ketones. The chiral alcohols were prepared in good to excellent yields (up to 99%) and were f
New iridium complex as high-efficiency red phosphorescent emitter in polymer light-emitting devices
Liang, Bo,Jiang, Changyun,Chen, Zhao,Zhang, Xiuju,Shi, Huahong,Cao, Yong
, p. 1281 - 1286 (2006)
A new heteroleptic iridium complex Ir(1-piq)2pt with 1-phenylisoquinoline and 3-(pyridin-2′-yl)-1H-1,2,4-triazole was synthesized and characterized. The complex was incorporated into phosphorescent polymer light-emitting devices using polyhedral oligomeric silsesquioxane- terminated polyfluorene (PFO-poss) as a host polymer doped with 30% of electron transport materials 2-(4-biphenylyl)-5-(4-tert-butylphenyl)-1,3,4-oxadiazole (PBD). Red electrophosphorescence was observed with a peak emission at 605 nm. The highest-efficiency polymer light-emitting diode was achieved with PFO-poss doped with 2% Ir(1-piq)2pt. An external quantum efficiency of 10.4% and a luminous efficiency of 9.4 cd A-1 were obtained at 10.8 mA cm-2. These values were found to be 7.67% and 5.99 cd A-1 at 100 mA cm-2.
Supramolecular metal helicate structures with incomplete metal ion coordination
Thompson,Matthews,Zhao,Wilson,Leech,Howard
, p. 2258 - 2262 (2001)
Two flexible 'polytopic' ligands take part in self assembly reactions with Ni(II) salts to produce helical structures, with 'incomplete' metal ion coordination, and the occupancy of empty coordination pockets by a water molecule and a putative fluoride ion. [Ni3(pd2am-H)3(H2O)](NO3) 3·2H2O 1 consists of a localized Ni2(N-N)3 dinuclear centre with three N-N single bond bridges, and a distant mono-nuclear Ni(II) centre, within the same molecular ion, and [Ni2(2pzoap)3F](BF4)3 ·8.5H2O 2 has a dinuclear stucture with two well separated octahedral Ni(II) sites. In both cases a single entity (H2O 1, F- 2) occupies a potential coordination pocket. Antiferromagnetic coupling is observed between the adjacent Ni(II) centres in 1, associated with the N-N bridging interactions, but the distant metal centres in 2 are uncoupled.
Self-assembled polymetallic square grids ([2 × 2] M4, [3 × 3] M9) and trigonal bipyramidal clusters (M5) - Structural and magnetic properties
Dawe, Louise N.,Abedin, Tareque S. M.,Kelly, Timothy L.,Thompson, Laurence K.,Miller, David O.,Zhao, Liang,Wilson, Claire,Leech, Michael A.,Howard, Judith A. K.
, p. 2645 - 2659 (2006)
New self-assembled grids and clusters are reported, with square [2 × 2] M4 (M = Mn(ii)4, Cu(ii)4), trigonal-bipyramidal Mn(ii)5, and square [3 × 3] M9 (M = Mn(ii), Cu(ii)) examples. These are based on a series of ditopic and tritopic hydrazone ligands involving pyridine, pyrimidine and imidazole end groups. In all cases the metal centres are bridged by hydrazone oxygen atoms with large (>125°) bridge angles, leading to antiferromagnetic exchange for all the Mn systems (J = -2 to -5 cm-1), which results in S = 0 (Mn4), and S = 5/2 (Mn5, Mn9) ground states. The copper systems have a 90° alternation of the Jahn-Teller axes within the Cu4 and Cu8 grid rings (Cu9), which leads to magnetic orbital orthogonality, and dominant ferromagnetic coupling. For the Cu9 grid antiferromagnetic exchange between the ring and the central copper leads to a S = 7/2 ground state, while for the Cu4 grids S = 4/2 ground states are observed. The magnetic data have been treated using isotropic exchange models in the cases of the Cu4 and Cu9 grids, and the Mn5 clusters. However due to the enormity of a fully isotropic calculation a simplified model is used for the Mn9 grid, in which the outer Mn8 ring is treated as the equivalent of an isolated magnetic chain, with no coupling to the central metal ion. The Royal Society of Chemistry 2006.
