110429-45-3

Basic information

• Product Name: Triethylene Glycol 2-Bromoethyl Methyl Ether
• Synonyms: Triethylene Glycol 2-Bromoethyl Methyl Ether;2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethyl Bromide 1-Bromo-3,6,9,12-tetraoxatridecane;m-PEG4-bromide;Methyl-PEG4-bromide;Bromo-PEG4-methoxy;13-Bromo-2,5,8,11-tetraoxatridecane;mPEG4-Br
• CAS NO: 110429-45-3
• Molecular Formula: C₉H₁₉BrO₄
• Molecular Weight: 271.149
• Mol File: 110429-45-3.mol

Chemical Properties

• Boiling Point: 296.3°C at 760 mmHg
• Flash Point: 118.8°C
• Appearance: /
• Density: 1.256g/cm³
• Vapor Pressure: 0.00256mmHg at 25°C
• Refractive Index: 1.4620 to 1.4660
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Triethylene Glycol 2-Bromoethyl Methyl Ether(CAS DataBase Reference)
• NIST Chemistry Reference: Triethylene Glycol 2-Bromoethyl Methyl Ether(110429-45-3)
• EPA Substance Registry System: Triethylene Glycol 2-Bromoethyl Methyl Ether(110429-45-3)

Safety Data

• Hazardous Substances Data: 110429-45-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Triethylene Glycol 2-Bromoethyl Methyl Ether is used as a synthetic intermediate for the development of various pharmaceutical compounds. Its unique structure, with a bromide leaving group and hydrophilic PEG spacer, makes it a valuable building block in the synthesis of drugs with improved solubility and bioavailability.
Used in Chemical Synthesis:
In the field of chemical synthesis, Triethylene Glycol 2-Bromoethyl Methyl Ether serves as a versatile reagent for nucleophilic substitution reactions. The presence of the bromide group allows for the easy introduction of various functional groups, enabling the creation of a wide range of molecules with specific properties and applications.
Used in Drug Delivery Systems:
Triethylene Glycol 2-Bromoethyl Methyl Ether is used as a component in the design of drug delivery systems. Its hydrophilic PEG spacer can improve the solubility and stability of drug carriers, such as nanoparticles or liposomes, in aqueous environments. This enhances the overall performance of the drug delivery system, leading to better therapeutic outcomes.
Used in Material Science:
In material science, Triethylene Glycol 2-Bromoethyl Methyl Ether can be utilized as a modifier or additive to improve the properties of various materials. The hydrophilic PEG spacer can enhance the compatibility of the material with aqueous environments, while the bromide group can facilitate further chemical modifications to tailor the material's characteristics for specific applications.

InChI:InChI=1/C9H19BrO4/c1-11-4-5-13-8-9-14-7-6-12-3-2-10/h2-9H2,1H3

Upstream product

• 109-86-4 2-methoxy-ethanol 
• 31255-10-4 1,2-bis-(2-bromo-ethoxy)-ethane 
• 23783-42-8 tetraethylene glycol monomethyl ether 
• 130955-37-2 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethyl) methanesulfonate 
• 112-60-7 Tetraethylene glycol 

Downstream Products

• 1012326-22-5 13,13'-(3,6-diiodo-1,2-phenylene)bis(oxy)bis(2,5,8,11-tetraoxatridecane) 
• 1246398-04-8 2,5-bis-(2-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethoxy)terephthalaldehyde 
• 1238836-02-6 C₂₅H₃₆N₂O₄S 

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