- Preparation method of pranlukast intermediate
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The invention provides a preparation method of a pranlukast intermediate. A compound C serving as a raw material reacts obtain the pranlukast intermediate. The preparation method has the advantages that the reaction condition is relatively mild, the operation is convenient, the purity and the yield of the obtained pranlukast intermediate are high, and the method is suitable for industrial production, so that a more valuable synthesis route is provided for preparation of pranlukast, good social benefits and economic benefits can be generated, and the economic potential is great.
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- Benzopyran derivatives having leukotriene-antagonistic action
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The present invention relates to novel 4-oxo-4H-1-benzopyran compounds containing benzyloxymethyl, 3-phenylpropyl, or other araliphatic substituents in their 8-position. These compounds show a leukotriene-antagonistic activity. The compounds are characterized by good oral adsorption. The compounds of the present invention may be used as anti-inflammatory and antiallergic medicaments, and in the treatment of cardiovascular diseases.
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- Process for preparing benzopyran compounds
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The present invention relates to a process for preparing compounds of structure (I), and the intermediate compound of formula (II).
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