- Ein einfaches Verfahren zur Herstellung von Organozinnaziden. Synthese und Struktur der sterisch gehinderten Stannylazide tBu3SnN3 und tBu2Sn(N3)2
-
Sterically crowded stannyl azides tBunSn(N3)4-n (IIa,b) have been prepared for the first time by the reactions of stannylamines tBunSn(NHR)4-n (Ia,b) with Me3SiN3 (a: n = 3, R = H; b: n = 2, R = tBu).The novel compounds were characterized by NMR (1H, 13C) and mass spectroscopy and their molecular structure determined by X-ray crystallography (IIa: space group P21/m, Z = 2; IIb: space group P21/n, Z = 4). Keywords: Tin; Stannyl azides; Synthesis; X-ray structure
- Haenssgen, Dieter,Jansen, Martin,Leben, Christiane,Oster, Thomas
-
-
Read Online
- SUBSTITUTED PYRIDOPYRIMIDINONES AND RELATED HETEROCYCLES AS ANGIOTENSIN II ANTAGONISTS
-
Novel substituted pyridopyrimidinones of formula (I), which are useful as angiotensin II antagonists, are disclosed. STR1
- -
-
-
- Substituted imidazo-fused 6-membered heterocycles as angiotensin II antagonists
-
Substituted Imidazo-fused 6-membered heterocycles of structural formula: STR1 wherein A, B, C, and D are independently carbon atoms or nitrogen atoms are angiotensin II antagonists useful in the treatment of hypertension and congestive heart failure.
- -
-
-
- IMIDAZOLE DERIVATIVES BEARING ACIDIC FUNCTIONAL GROUPS AT THE 5-POSITION, THEIR COMPOSITIONS AND METHODS OF USE AS ANGIOTENSIN II ANTAGONISTS
-
There are disclosed substituted imidazole derivatives of Formula I bearing acidic functional groups which are useful as angiotensin II antagonists. STR1
- -
-
-
- SUBSTITUTED PYRAZOLOPYRIMIDINES AS ANGIOTENSIN II ANTAGONISTS
-
Novel substituted pyrazolopyrimidines of formula (I) which are useful as angiotensin II antagonists, are disclosed. STR1
- -
-
-
- Substituted pyrazino 2,3-D pyrimidinones as angiotensin II antagonists
-
Novel substituted pyrazino[2,3-d]pyrimidinones of formula (I), are angiotensin II antagonists, useful in the treatment of hypertension and related disorders and in certain CNS disorders.
- -
-
-
- Substituted quinazolinones as angiotensin II antagonists
-
Novel substituted quinazolinones of the formula (I), which are useful as angiotensin II antagonists, are disclosed. STR1
- -
-
-
- MICROBIAL TRANSFORMATION PROCESS FOR PRODUCING AN ANTIHYPERTENSIVE PRODUCT
-
Fermentation of the microorganism Streptomyces sp. (MA6750) ATCC No. 55042 in the presence of the Angiotensin II (A II) receptor antagonist of the following structure: STR1 yields an analog having a shikimate sugar-like moiety attached to the tetrazole, the said analog which is also an A II antagonist useful in the treatment of hypertension and congestive heart failure and other indications known to respond to A II angatonists.
- -
-
-
- SUBSTITUTED IMIDAZO-FUSED 6-MEMBERED HETEROCYCLCES AS ANGIOTENSIN II ANTAGONISTS
-
Substituted Imidazo-fused 6-membered heterocycles of structural formula: STR1 wherein A, B, C, and D are independently carbon atoms or nitrogren atoms are angiotensin II antagonists useful in the treatment of hypertension and congestive heart failure.
- -
-
-
- Microbial transformation process for antihypertensive products
-
Fermentation of the microorganism Streptomyces sp. MA6751 (ATCC No. 55043) in the presence of the Angiotensin II (A II) receptor antagonist yields an N2-tetrazole β-glucuronide analog which is also an A II antagonist useful in the treatment of hypertension and congestive heart failure and other indications known to respond to A II antagonists.
- -
-
-
- Anti-hypersensitive N2-tetrazole-β-glucuronide analog
-
Fermentation of the microorganism Streptomyces sp. MA6751 in the presence of STR1 yields an anti-hypertensive compound of the structure STR2
- -
-
-
- MICROBIAL TRANSFORMATION PROCESS FOR PREPARING ANTI-HYPERTENSIVE PRODUCTS
-
Fermentation of the microorganism Streptomyces sp. (MA6750) ATTC No. 55042 in the presence of the Angiotensin II (A II) receptor antagonist STR1 yields three analogs, each having a shikimate sugar-like moiety attached to the tetrazole, which are also A II antagonists useful in the treatment of hypertension and congestive heart failure and other indications known to respond to A II antagonists.
- -
-
-
- Antihypertensive products, a process for their preparation and pharmaceutical compositions containing them.
-
Fermentation of the microorganism Actinoplanacete sp. in the presence of the Angiotensin II (A II) receptor antagonist yields a 5-hydroxymethyl and a 7-hydroxymethyl analog, both of which are also A II antagonists useful in the treatment of hypertension and congestive heart failure and other indications known to respond to A II antagonists.
- -
-
-
- Angiotensin II antagonists
-
Novel substituted imidazo-fused 7-member ring heterocycles of the formulae (I) and (Ia), which are useful as angiotensin II antagonists, are disclosed. STR1
- -
-
-
- Substituted benzimidazoles as angiotensin II antagonists
-
There are disclosed new substituted benzimidazole compounds and derivatives thereof which are useful as angiotensin II antagonists. These compounds have the general formula:
- -
-
-