1122568-09-5

Basic information

• Product Name: 2-(2-Methoxyethoxy)phenylboronic acid
• Synonyms: 2-(2-Methoxyethoxy)phenylboronic acid;[2-(2-METHOXYETHOXY)PHENYL]BORANEDIOL
• CAS NO: 1122568-09-5
• Molecular Formula: C₉H₁₃BO₄
• Molecular Weight: 196.00812
• Product Categories: Boronate Ester;Boronic Acid;Potassium Trifluoroborate
• Mol File: 1122568-09-5.mol

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 2-(2-Methoxyethoxy)phenylboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Methoxyethoxy)phenylboronic acid(1122568-09-5)
• EPA Substance Registry System: 2-(2-Methoxyethoxy)phenylboronic acid(1122568-09-5)

Safety Data

• Hazardous Substances Data: 1122568-09-5(Hazardous Substances Data)

Usage

Uses

2-(2-Methoxyethoxy)phenylboronic acid is a useful intermediate for organic synthesis.

Upstream product

• 150-46-9 triethyl borate 
• 7664-93-9 sulfuric acid 
• 109417-60-9 1-bromo-2-(2-methoxyethoxy)benzene 
• 194367-88-9 1-iodo-2-(2-methoxyethoxy)benzene 

Downstream Products

• 1174929-43-1 2-chloro-1-[2-(2-methoxy-ethoxy)-phenyl]-1H-indole-3-carbaldehyde 

Relevant articles and documents

Hydrogen bonds in phenylboronic acids with polyoxaalkyl substituents at ortho-position

Phenylboronic acids with polyoxaalkyl substituents at ortho position were synthesized from the corresponding bromides. Structures in solid state, determined by single crystal X-ray diffraction, reveal the presence of inter- and intramolecular hydrogen bonds. Presence of several oxygen atoms in oxaalkyl chains enables the formation of intramolecular hydrogen bonds by B(OH)2 group with different oxygen centers which lead to the formation of bifurcated hydrogen bonds. Investigated compounds were characterized by 1H, 13C, 11B and 17O NMR spectroscopy in solution. Assignment of 1H and 13C signals was made on the basis of HSQC and HMBC spectra. 17O NMR spectra show that in acetonitrile solution hydrogen bonds with solvent molecules are predominant.

CYCLIC INDOLE-3-CARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS

The present invention relates to cyclic indole-3-carboxamides of the Formula (I), wherein A, R, R10, R20, R30, R40, n, p and q have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. Specifically, they inhibit the enzyme renin and modulate the activity of the renin-angiotensin system, and are useful for the treatment of diseases such as hypertension, for example. The invention furthermore relates to processes for the preparation of the compounds of the Formula (I), their use and pharmaceutical compositions comprising them.

RENIN INHIBITORS

The present invention relates to biphenyl compounds of formula (I). These compounds are renin inhibitors of a non- peptidic nature and of low molecular weight. The invention further relates to a pharmaceutical composition containing said compounds, as wel