194367-88-9Relevant articles and documents
Synthesis of 2H-1-benzopyrans via palladacycles with a metal-bonded stereogenic carbon
Portscheller, Janelle L.,Malinakova, Helena C.
, p. 3679 - 3681 (2002)
(graph presented) Stable oxapalladacycles have been prepared and converted into a series of highly functionalized 2H-1-benzopyrans via regioselective insertion of activated alkynes.
CYCLIC INDOLE-3-CARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS
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Page/Page column 82, (2009/09/05)
The present invention relates to cyclic indole-3-carboxamides of the Formula (I), wherein A, R, R10, R20, R30, R40, n, p and q have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. Specifically, they inhibit the enzyme renin and modulate the activity of the renin-angiotensin system, and are useful for the treatment of diseases such as hypertension, for example. The invention furthermore relates to processes for the preparation of the compounds of the Formula (I), their use and pharmaceutical compositions comprising them.