112970-57-7

Basic information

• Product Name: N-(2,4-dibromophenyl)-4-methylbenzenesulfonamide
• Synonyms: benzenesulfonamide, N-(2,4-dibromophenyl)-4-methyl-
• CAS NO: 112970-57-7
• Molecular Formula: C₁₃H₁₁Br₂NO₂S
• Molecular Weight: 405.1049
• Mol File: 112970-57-7.mol

Chemical Properties

• Boiling Point: 463.5°C at 760 mmHg
• Flash Point: 234.1°C
• Density: 1.783g/cm³
• Vapor Pressure: 9.06E-09mmHg at 25°C
• Refractive Index: 1.661
• CAS DataBase Reference: N-(2,4-dibromophenyl)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,4-dibromophenyl)-4-methylbenzenesulfonamide(112970-57-7)
• EPA Substance Registry System: N-(2,4-dibromophenyl)-4-methylbenzenesulfonamide(112970-57-7)

Safety Data

• Hazardous Substances Data: 112970-57-7(Hazardous Substances Data)

Upstream product

• 615-57-6 2,4-dibromo-aniline 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 112970-69-1 1-toluenesulfonyl-5-vinyl-1H-indole 

Relevant articles and documents

Directing-group-assisted markovnikov-selective hydrothiolation of styrenes with thiols by photoredox/cobalt catalysis

In contrast with the well-developed radical thiol-ene reaction to access anti-Markovnikov-type products, the research on the catalytic Markovnikov-selective hydrothiolation of alkenes is very restricted. Because of the catalyst poisoning of metal catalysts by organosulfur compounds, limited examples of transition-metal-catalyzed thiol-ene reactions have been reported. However, in this work, a directing-group-assisted hydrothiolation of styrenes with thiols by photoredox/cobalt catalysis is found to proceed smoothly to afford Markovnikov-type sulfides with excellent regioselectivity.

Visible-Light-Driven Neutral Nitrogen Radical Mediated Intermolecular Styrene Difunctionalization

A neutral nitrogen radical-mediation strategy, wherein the existing N-H moiety of substrates serves as a neutral nitrogen radical precursor to enable room-temperature intermolecular radical difunctionalization of styrenes under photoredox catalysis, is reported. The reaction shows high functional group tolerance and substrate scope with respect to both components, giving the corresponding products with generally good yields. Preliminary control experiments and DFT calculations are performed to explain the reaction mechanism.

Palladium-Catalyzed Coupling of 2-Bromoanilines with Vinylstannanes. A Regiocontrolled Synthesis of Substituted Indoles

The palladium-catalyzed cross-coupling reaction of aryl halides and triflates with vinylstannane reagents has been used to produce a variety of substituted indoles.The mild reaction conditions and selectivity inherent in the coupling reaction have been utilized to produce regiochemically pure 4-, 5-, and 6-substituted indoles.