113308-95-5Relevant academic research and scientific papers
Silver(I)-catalysed protiodesilylation of 1-(Trimethylsilyl)-1-alkynes
Carpita, Adriano,Mannocci, Luca,Rossi, Renzo
, p. 1859 - 1864 (2007/10/03)
A procedure for protiodesilylation of 1-(trimethylsilyl)-1-alkynes that involves the use of catalytic amounts of AgNO3 and does not require the employment of KCN is described. This procedure allows for chemoselective deprotection of 1-(trimethylsilyl)-1-alkynes containing α-(trimethylsilyl) benzyl moieties, tert-butyldiphenylsilyl alkyl ethers or tert-butyldimethylsilyl aryl ether groups. However, it causes complete desilylation of l-(trimethylsilyl)-1-alkynes characterised by a primary alcoholic group protected as a tert-butyldimethylsilyl ether. Interestingly, compounds that contain this last functional group can also furnish the corresponding alcohols by treatment with a catalytic amount of aqueous HNO3. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005.
On the in situ trimethylsilylation of zinc acetylides
M?eorg, Uno,Viirlaid, S?de,Hagu, Hannes,Verkruijsse, Hermann D.,Brandsma, Lambert
, p. 341 - 342 (2007/10/03)
Reinvestigation of the recently published formation of silylated alkynes by reaction of 1-alkynes with zinc and trimethylchlorosilane in acetonitrile showed that appreciable amounts of 1-alkenes are formed as side products.
