113676-36-1

Basic information

• Product Name: 4-(2-aminoethyl)-2-fluorophenol hydrobromide
• CAS NO: 113676-36-1
• Molecular Formula: BrH*C₈H₁₀FNO
• Molecular Weight: 236.0814
• Mol File: 113676-36-1.mol

Chemical Properties

• Boiling Point: 252.6°C at 760 mmHg
• Flash Point: 106.6°C
• Vapor Pressure: 0.012mmHg at 25°C
• CAS DataBase Reference: 4-(2-aminoethyl)-2-fluorophenol hydrobromide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-aminoethyl)-2-fluorophenol hydrobromide(113676-36-1)
• EPA Substance Registry System: 4-(2-aminoethyl)-2-fluorophenol hydrobromide(113676-36-1)

Safety Data

• Hazardous Substances Data: 113676-36-1(Hazardous Substances Data)

Upstream product

• 404-90-0 2-(3-fluoro-4-methoxyphenyl)acetonitrile 
• 118958-80-8 2-fluoro-1-methoxy-4-(2-nitrovinyl)benzene 
• 351-54-2 3-fluoro-p-anisaldehyde 
• 458-40-2 2-(3-fluoro-4-methoxyphenyl)ethan-1-amine 

Relevant articles and documents

triAZOLOtriAZINE DERIVATIVES AS A2A RECEPTOR ANTAGONISTS

The present invention provides triazolotriazine derivatives of formula (1) as A2A receptor antagonists. Compounds of formula (1) and pharmaceutical compositions including the compounds can be used for the treatment of disorders related to A2A receptor hyperfunctioning, such as certain types cancers. Compounds of formula (1) and methods of preparing the compounds are disclosed in the invention.

Phenoxyacetic acid derivatives, pharmaceutical compositions and methods

Novel phenoxyacetic acid derivative of the formula: STR1 wherein R is a substituted or unsubstituted phenyl group, naphthyl group or a sulfur-containing 5-membered hetero-monocyclic group, R1, R2, R3 and R4 are hydrogen atom, a lower alkyl group, a phenyl-lower alkyl group or phenyl group, R5 is hydrogen atom or a lower alkyl group, R6 is carboxyl group, a protected carboxyl group, hydroxy group or a di(lower alkyl)-amino group, Ring A is a substituted or unsubstituted phenylene group, m is 0 or 1 and n is an integer 0 to 5, provided that, when m is 0, (1) at least either one of R1 to R4 is or/are a phenyl-lower alkyl group or phenyl group, (2) at least either one of R1 to R4 is or/are a lower alkyl group, and R6 is hydroxy group, or (3) all of R1 to R4 are hydrogen atom, and Ring A is a substituted phenylene group, or a pharmaceutically acceptable salt thereof are disclosed. Said derivative (I) and a pharmaceutically acceptable salt thereof have a potent platelet aggregation-inhibiting activity.

POTENTIAL ANTIDEPRESSANTS: 3-METHYL-6-DIMETHYLAMINO-1,2-DIPHENYLHEXAN-3-OL AND RELATED COMPOUNDS

3,4-Diphenylbutan-2-one (III) and 3-methyl-3-phenylbutan-2-one were transformed by treatment with 3-dimethylaminopropylmagnesium chloride and 1-methyl-4-piperidylmagnesium chloride to the amino alcohols VI, VII, and X.Compound VI was dehydrated to the ole