114569-19-6Relevant articles and documents
Design, synthesis and in vitro antimalarial evaluation of new quinolinylhydrazone derivatives
Thuy, Le Thi,Tien, Hoang Xuan,Hoang, Vu Dinh,Vu, Tran Khac
scheme or table, p. 163 - 168 (2012/07/17)
A series of novel quinolinylhydrazones (5a-f) was synthesized by the condensation reaction of 2,6-diaryl-substituted piperidin-4-ones (4a-f) with 7-chloro-4-hydrazinoquinoline (2). Novel quinolinylhydrazones containing Shiff bases 8a-f and 11a-f were obta
Highly efficient synthesis and characterization of the GPR30-selective agonist G-1 and related tetrahydroquinoline analogs
Burai, Ritwik,Ramesh, Chinnasamy,Shorty, Marvin,Curpan, Ramona,Bologa, Cristian,Sklar, Larry A.,Oprea, Tudor,Prossnitz, Eric R.,Arterburn, Jeffrey B.
experimental part, p. 2252 - 2259 (2010/07/03)
The GPR30 agonist probe G-1 and structural analogs were efficiently synthesized using multicomponent or stepwise Sc(iii)-catalyzed aza-Diels-Alder cyclization. Optimization of solvent and reaction temperature provided enhanced endo-diastereoselectivity.
Solid phase synthesis of aminochalcones
Yi, Fengping,Peng, Yanqing,Song, Gonghua,Li, Jizong
, p. 311 - 312 (2007/10/03)
A microwave-assisted solid phase synthesis of aminochalcones via the Claisen-Schmidt condensation reaction between resin-bound p-aminoacetophenone and aromatic aldehydes was described.
Synthesis of Some New &β-Lactams, 4-Thiazolidinones and Pyrazolines
Fahmy, A. M.,Hassan, Kh. M.,Khalaf, A. A.,Ahmed, R. A.
, p. 884 - 887 (2007/10/02)
N-Arylidene-p-aminoacetophenone (I) and N-arylidene-4'-aminochalcones (V) have been converted into a series of substituted β-lactams (III) and 4-thiazolidinones (IV), and pyrazolines (VI, VII) respectively. p-Chloroacetamidoacetophenone (II) has also been converted into series of substituted 4'-piperidino/morpholinoacetoamidochalcones (X) which undergo cyclization on treatment with hydrazine, phenylhydrazine or thiourea to pyrazolines (XI, XII) and pyrimidine-2-thiones (XIII) respectively.The antibacterial and antifungal activities of the compounds have been determined.